In diastolic dysfunction, the diastolic pressure-volume relationship is shifted upward and to the left (dashed line), which leads to an elevated left ventricular end-diastolic pressure a and reduced stroke volume. (Reproduced, with permission, from McPhee SJ et al [editors]. Pathophysiology of Disease: An Introduction to Clinical Medicine, 3rd ed. McGraw-Hill, 1999.) Source: Heart Disease, Current Medical Diagnosis & Treatment 2018 Citation: Papadakis MA, McPhee SJ, Rabow MW. Current Medical Diagnosis & Treatment 2018; 2017 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/2192/cmdt18_ch10_ef106-1.png&sec=168191893&BookID=2192&ChapterSecID=168190671&imagename= Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved