Vasculitis versus vessel caliber

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ANCA disease: immunoserology and pathogenesis Alenka Vizjak Institute of Pathology · Faculty of Medicine University of Ljubljana, Ljubljana, Slovenia.

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Presentation transcript:

Vasculitis versus vessel caliber Vasculitis versus vessel caliber. Distribution of vessel involvement by large-vessel vasculitis, medium-vessel vasculitis, and small-vessel vasculitis. Note that there is substantial overlap with respect to arterial involvement, and an important concept is that all three major categories of vasculitis can affect any size artery. Small-vessel vasculitis predominantly affects small vessels, but medium arteries and veins may be affected, although immune complex small-vessel vasculitis rarely affects arteries. The diagram depicts (from left to right) aorta, large artery, medium artery, small artery/arteriole, capillary, venule, and vein. Anti-GBM, antiglomerular basement membrane; ANCA, antineutrophil cytoplasmic antibody. From Jennette JC, Falk RJ, Bacon PA, et al. 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65(1):1–11 (Figure 17). Source: The Vascular System, Pathology: A Modern Case Study Citation: Reisner HM. Pathology: A Modern Case Study; 2015 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/Books/1569/rei_ch7_f015.png&sec=95969052&BookID=1569&ChapterSecID=95968984&imagename= Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved