A rare case of concurrent myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO- ANCA)-associated necrotising and crescentic glomerulonephritis and.

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Presentation transcript:

A rare case of concurrent myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO- ANCA)-associated necrotising and crescentic glomerulonephritis and membranous glomerulonephritis Chow Heok P'ng, Levina Dear, Richard Phoon, David Brown Pathology Volume 49, Issue 1, Pages 100-103 (January 2017) DOI: 10.1016/j.pathol.2016.10.008 Copyright © 2016 Terms and Conditions

Fig. 1 (A) Necrotising and crescentic glomerulonephritis. (B) Vasculitis featuring segmental fibrinoid necrosis in vessel wall. Pathology 2017 49, 100-103DOI: (10.1016/j.pathol.2016.10.008) Copyright © 2016 Terms and Conditions

Fig. 2 Immunofluorescence IgG staining along the glomerular capillary wall. Pathology 2017 49, 100-103DOI: (10.1016/j.pathol.2016.10.008) Copyright © 2016 Terms and Conditions

Fig. 3 (A) Stage 3 membranous glomerulonephritis (electron microscopy) showing subepithelial electron-dense deposits incorporated in the thickened GBM. (B) Dissolution of subepithelial deposits which are embedded within the thickened GBM. Pathology 2017 49, 100-103DOI: (10.1016/j.pathol.2016.10.008) Copyright © 2016 Terms and Conditions