From: Muscarinic Signaling in the Central Nervous System:Recent Developments and Anesthetic Implications Anesthes. 1996;84(1):173-189. Figure Legend: Figure.

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From: Muscarinic Signaling in the Central Nervous System:Recent Developments and Anesthetic Implications Anesthes. 1996;84(1):173-189. Figure Legend: Figure 4. Distribution of muscarinic receptor subtype mRNA and choline-O-acetyltransferase mRNA in rat brain. Subtype-selective oligonucleotide probes were hybridized to horizontal sections of rat brain. The pictures are photomicrographs from film autoradiograms, where dark regions correspond to areas rich in hybridization material. Sections shown in (A), (B), (C), (D), and (F) are very close to each other, whereas the section shown in (E) is more ventral to illustrate the presence of m5 mRNA in the subtantia nigra and ventral tegmental area. m1 and m4 are found primarily in cortical areas, whereas m2 and m3 are found in deeper structures. Acb = nucleus accumbens; Amg = amygdala; AM = anteromedial thalamic nucleus; AV = anteroventral thalamic nucleus; B = cells of the basal nucleus of Meynert; CM = central medial thalamic nucleus; CPu = caudate-putamen; Hp = hippocampus; LDTg = laterodorsal tegmental nucleus; MS = medial septal nucleus; olf = olfactory bulb; Rt = reticular thalamic nucleus; SNC = substantia nigra pars compacta; VTA = ventral tegmental area; 3,4 = oculomotor and trochlear nuclei. Bar = 5 mm. From Vilaro et al. *RF 171 Date of download: 10/29/2017 Copyright © 2017 American Society of Anesthesiologists. All rights reserved.