BME 130 – Genomes Lecture 1 History of Genomics.

Slides:

Advertisements

Similar presentations

History of Genetics People have known about inheritance for a long time. --children resemble their parents --domestication of animals and plants, selective.

Advertisements

Mendel- worked with pea plants and discovered the laws of heredity (work was ignored until 1900 when rediscovered) Meischer- discovered DNA, called nuclein,

基因工程與原理 GENE CLONING & DNA ANALYSIS T. A. BROWN 許勝傑博士長庚大學生物醫學系助理教授生物醫學研究所生化暨細胞分子生物學組分子細胞與腫瘤研究室電話 (03) #3690.

Themes in the Development of DNA Science A short history of Molecular Biology.

BIOLOGY 12 Genetics: An Introduction. A little motivational video:

Biotechnology Timeline

History of Genetics People have known about inheritance for a long time. Children resemble their parents Domestication of animals and plants, selective.

Medical Genetics in 2020? What will we be able to do? What should we be able to do?

Genetica per Scienze Naturali a.a prof S. Presciuttini 1. The laws of inheritance 1866: Gregor Mendel publishes his findings on the laws of inheritance.

PLANT MOLECULAR GENETICS

Bio 344 Molecular Biology Old web site: bio344/

BME 130 – Genomes Lecture 1 History of Genomics.

History of Genetics People have known about inheritance for a long time. --children resemble their parents --domestication of animals and plants, selective.

E. coli Genetics: From Genes to Genomes. Figure 4.1a: Gregor Mendel © National Library of Medicine.

Origins of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

--- History of Molecular Biology

MCB 7200: Molecular Biology

The History of Genetics From classical genetics to the personal human genome.

Lecture 1 Introduction to recombinant DNA Technology Dr Muhammad Imran.

Historical perspectives- Early evidence , DNA is the genetic material

The History and Science of Molecular Genetics Timothy G. Standish, Ph. D.

Overview of Biological Problems History Human disease Key biology research areas Model organisms Research methods in biology.

History of Genetics By: Keith King

Robert Hooke discovers compartments he calls ‘cells’ in cork Anton Van Leeuwenhoek produced microscopes of 200x magnification Robert.

Outline of Modern Genetics ► Jean Baptiste Lamarck (French, early 19 th c.): “The Inheritance of Acquired Characteristics” ► Charles Darwin (English, 1859):

DNA: the story behind the molecule

UNIT 3 The transmission of traits Biology and Geology. Secondary Education. THE CHROMOSOME THEORY OF INHERITANCE.

MANDATORY READING THE PLANT AND ANIMAL CELL Diversity between individuals Diversity Among individuals.

UNIT 2: Mechanisms of Inheritance

Copyright © 2010 Pearson Education Inc. Lecture 01 – Genetics & Genomics: An Introduction Based on Chapter 1 – Genetics: An introduction.

MCB 720: Molecular Biology Biotechnology terminology Common hosts in biotechnology research Transcription & Translation Prokaryotic gene organization &

 HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential.

A brief history of Molecular biology. Big names Charles Darwin ( ) On the origin of species by means of the natural selection (1859)

MCB 720: Molecular Biology Biotechnology terminology Common hosts in biotechnology research Transcription & Translation Prokaryotic gene organization &

Algorithms for Biological Sequence Analysis Kun-Mao Chao ( 趙坤茂 ) Department of Computer Science and Information Engineering National Taiwan University,

MCB 7200: Molecular Biology Biotechnology terminology Common hosts and experimental organisms Transcription and translation Prokaryotic gene organization.

Genetics Slides courtesy of Maureen Giacomazza , RN

INTRODUCTION TO PLANT MOLECULAR GENETICS. Why young breeders must study genetics?

 HS-LS1-1. Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential.

DNA Timeline The discovery of Genetics and DNA

HISTORICAL EXPERIMENTAL EVENTS IN BIOTECHNOLOGY RESEARCH & DEVELOPMENT Revised June 2010.

Genetics: Introductory Notes. Principal Points: Genetics can be divided into 4 subdisciplines – Transmission genetics – passage of genes from generation.

Introduction -1 1 Lecture no.1 BCH 361/ Section: xxxxx.

THE FOUNDATIONS: Gregor Mendel’s paper on hybridisation in pea plants was published in 1865, but no-one recognised its significance until Charles.

Genetic technology. Biotechnology Alteration of cells or molecules for specific application. Genetic engineering refers to any biotechnology that manipulates.

REVIEW ______________________ contains all the genetic instructions to create all the cells in your body. What Does DNA stand For? ________ -part of a.

On the Origin of Species 1859 Inheritance of acquired characteristics 1809.

History of Genetics By: Keith King. Objectives State the history of genetics; Describe major century events; Define terms used in genetics.

All Your Hopes and All Your Fears

History of Genetics People have known about inheritance for a long time. --children resemble their parents --domestication of animals and plants, selective.

Warm up View Video and list all the biotechnical things the family uses.

LECTURE Schedule 1. An Introduction: – 9. 6

Biotechnology Timeline

GENETICS AND MOLECULAR BIOLOGY

Biotechnology Timeline

Warm up View Video and list all the biotechnical things the family uses.

Lecture 1 Introduction to recombinant DNA Technology

Opening the book of life … or Pandora’s box?

Algorithms for Biological Sequence Analysis

Biotechnology Timeline

DNA: the story behind the molecule

What is RNA Hypothesis world?

Lecture #1: Introduction to Genetics and Cells

Genetic Engineering – can

Biotechnology and Genetic Engineering PBIO 450/550

Biotechnology Timeline

Introduction to Genetics and Breeding

Genesis 1:26 26 And God said, Let us make man in our image, after our likeness: and let them have dominion over the fish of the sea, and over the fowl.

Plant Molecular Biology

Presentation transcript:

BME 130 – Genomes Lecture 1 History of Genomics

Course policies Grading Group (paper presentations; class assignments) Course overview website?

Charles Darwin On the Origin of Species 1859 Gregor Mendel Experiments in Plant Hybridisation 1866

Statistical genetics, law of ancestral heridity (basis of eugenics) Francis Galton Statistical genetics, law of ancestral heridity (basis of eugenics) 1876 Propose that hereditary factors reside on chromosomes and are inherited by Mendellian laws (1902) Walter Sutton Theodor Boveri

Archibald Garrod Alkaptonuria is not caused by bacterial infection, but is inherited (recessive), 1908 Thoman Hunt Morgan Experimental validation of chromosomal theory of inheritance, established fruit fly as model genetic organism, 1910

Crick enunciates central dogma of molecular biology 1957 James Watson and Francis Crick describe a model for the structure of DNA, 1953; Crick enunciates central dogma of molecular biology 1957

Marshall Nirenberg Cracks the genetic code by translating (first) poly-U, 1961

Paul Berg Creates first recombinant DNA molecules, 1972

Herber Boyer and Stan Cohen Clone DNA into foreign cells; birth of recombinant DNA technology, 1973

Walter Gilbert and Fred Sanger Develop methods to sequence DNA, 1977

Kary Mullis Invents the polymerase-chain reaction for DNA amplification, 1983

Scheibye-Alsing et al. (2009), Comp. Biology & Chemistry 33(2):121

Genomes! 1995 Hemophilus influenzae 1996 yeast 1998 worm 1999 fruit fly 2001 human 2002 mouse 2004 rat http://www.genomenewsnetwork.org/