From: Pharmacokinetic Analysis of Melphalan after Superselective Ophthalmic Artery Infusion in Preclinical Models and Retinoblastoma Patients Invest. Ophthalmol. Vis. Sci.. 2012;53(7):4205-4212. doi:10.1167/iovs.12-9501 Figure Legend: Dose-dependent cytotoxicty of melphalan in (A) Y79 and (B) WERI-RB retinoblastoma cell lines. Data are presented as mean ± SEM of duplicate experiments done in triplicates. The insets show the effect of topotecan 10 nM on melphalan cytotoxicty of both cell lines. Date of download: 10/29/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.