Central role for Cdc42 in yeast budding

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Presentation transcript:

Central role for Cdc42 in yeast budding Park and Bi, 2007

Conserved polarity elements Thompson, 2013

Early asymmetry in C. elegans Kemphues, 2000

Par proteins and asymmetry Munro and Bowerman, 2009

Asymmetry of cell division

Asymmetric distribution of par proteins Par6-GFP Par2-GFP Munro et al., 2004 Schonegg and Hyman, 2006

Asymmetric myosin and Cdc42 flow Nmy2-GFP Cdc42-GFP Munro et al., 2004 Schonegg and Hyman, 2006

Jenkins et al., 2006

Thompson, 2013

Epithelial organs form lumens

The three epithelial polarity complexes Humbert et al., 2008

PIP distribution in migrating cells

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