Change is the Fabric of Life Evolution of INTERMACS & MCSD INTERMACS 10TH Annual Meeting James B, Young, M.D. Study Chair March 12, 2016

The Challenge of MCSD Surgery

MED-LVAD 1966 50 years ago Follow up

ADVANCED HEART FAILURE

MCSD Evolution

PARADIGM SHIFT PARADIGM: example or pattern Thomas Kuhn The Structure of Scientific Revolutions (1962) Paradigm shift = “extraordinary” or “revolutionary” science “…once a paradigm shift is complete, a scientist cannot, for example, posit the possibility that a miasma causes disease or that ether carries light.” Science vs the humanities – how do you look at things?

Pope Julius II/Raphael – “School of Athens” 1510 Democratus Heraclitus Pope Julius II/Raphael – “School of Athens” 1510 JBY

CHANGE IS THE FABRIC OF LIFE “To improve is to change; to be perfect is to change often” Winston Churchill “Even if you are on the right track, you'll get run over if you just sit there” Will Rogers Heraclitus – “…universal doctrine of change.” Raphael – “School of Athens” 1510

Bye Bye Borders (RIP; 1971-2011) Bob Dylan “…you’d better start swimming or you’ll sink like a stone…for the times they are a-changin!” (1964) 2006 Bye Bye Borders (RIP; 1971-2011)

Bob Dylan “…you’d better start swimming or you’ll sink like a stone…for the times they are a-changin!” (1964) 2006

Not the LEAD DOG? The view won’t CHANGE…