Chemical leukoderma. A. O-Syl (a phenolic disinfectant)-induced chemical leukoderma that mimics vitiligo clinically. Repeated exposure is required to depigment, but antecedent clinical inflammation is not observed. B. Reversible hypomelanosis of the face in a South African woman after several weeks’ application of topical hydroquinone. Note color contrast of face to that of (untreated) hand. C. African-American factory worker depigmented from repeated exposure to monobenzyl ether of hydroquinone. Source: Chapter 75. Hypomelanoses and Hypermelanoses, Fitzpatrick's Dermatology in General Medicine, 8e Citation: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K. Fitzpatrick's Dermatology in General Medicine, 8e; 2012 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/gold8/gold8_c075f009.png&sec=41146130&BookID=392&ChapterSecID=41138777&imagename= Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved