Outline. Adherence in the Age of HCV Antivirals: Lessons from HIV Adherence Interventions.

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Presentation transcript:

Adherence in the Age of HCV Antivirals: Lessons from HIV Adherence Interventions

Outline

Introduction

Adherence to HCV Therapy

Adherence and EVR

Adherence and SVR

Adherence Over Time

Implications

Outline

Fluidity of Adherence Barriers

Risk Factors (I)

Risk Factors (II)

Provider Prediction

Outline

Adherence Interventions

Intervention Strategies

Adherence and Directly Observed Therapy (DOT)

Metaanalysis of DOT in HIV

Cellphone-Based Interventions

WelTel Kenya1 Results

Cellphone Conclusions

Managed Problem Solving (MAPS)

Defining the Problem

Brainstorm

Decision re: Plan

Implement Plan

Assessment and Modification

MAPS Study Design

Baseline Screening

Delivery of Intervention

November 2011

Overall Adherence Results

Overall VL Results

Conclusions and Next Steps

Outline

Intervention Lessons

Future Needs

What Should HCV Providers Do Now?

Conclusions

Acknowledgements

Thank you, study participants!