Can osteoprotegerin be used to identify the presence and severity of coronary artery disease in different clinical settings? Susanne Elisabeth Hosbond,

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Can osteoprotegerin be used to identify the presence and severity of coronary artery disease in different clinical settings? Susanne Elisabeth Hosbond, Axel Cosmus Pyndt Diederichsen, Lotte Saaby, Lars Melholt Rasmussen, Jess Lambrechtsen, Henrik Munkholm, Niels Peter Rønnow Sand, Oke Gerke, Tina Svenstrup Poulsen, Hans Mickley Atherosclerosis Volume 236, Issue 2, Pages 230-236 (October 2014) DOI: 10.1016/j.atherosclerosis.2014.07.013 Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Box plot of OPG concentrations in clinical groups excluding outliers. The box represents the 25th and 75th percentile; the middle line represents the median and the peripheral lines extend to the outer fences which are 1.5 times the interquartile range below and above the 25th and 75th percentile, respectively. OPG: Osteoprotegerin; Score = Agatston Score; No CAD = No coronary artery disease; Non-sign. CAD: Non-significant coronary artery disease; Sign. CAD: Significant coronary artery disease; Acute MI: Acute myocardial infarction. Atherosclerosis 2014 236, 230-236DOI: (10.1016/j.atherosclerosis.2014.07.013) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 ROC curve illustrating OPG in patients with CAD and those without CAD on angiography. ROC: Receiver operator characteristics; OPG: Osteoprotegerin; CAD: Coronary artery disease. Atherosclerosis 2014 236, 230-236DOI: (10.1016/j.atherosclerosis.2014.07.013) Copyright © 2014 Elsevier Ireland Ltd Terms and Conditions