Day Date Reading Topic Th 11/28 no class – Thanksgiving Break T 12/3 Ch. 12 more on Neurogenesis Th 12/5 Ch. 9 The Saga of the Germ Line T 12/10 more on Reproduction quiz on Tues: Draw and Describe pathfinding in any animal CNS Th 12/12 parts of Ch. 13 Growth   in class assignment on Thurs: build an Edible Urbilaterian Ancestor you can bring extra ingredients The Final Exam will be in our regular classroom on Friday, Dec. 20th, 8:00 – 10:00 AM. The exam will cover all the material in the course. Also remember there are two, short writing assignments, each worth 20 points. Pick any topic in developmental biology (except your term paper topic) and learn more about it. Then write a two page paper and include all the sources you used (those can include any sources including web sites, newspapers, TV, etc). These are due anytime.

Final Exam covers the whole course

Final Exam covers the whole course early vertebrate development what frog and chick early embryos look like Drosophila dorsal – ventral patterning vertebrate limb development neurobiology Notch signaling early neurogenesis pathfinding reproduction: germline steps in fertilization

12.18 growth cone guidance

http://en.wikipedia.org/wiki/Urbilaterian http://palaeos.com/metazoa/bilateria.htm

1) PATHFINDING INSIDE THE CNS 2) PATHFINDING OUTSIDE THE CNS 12.17 neuron growth cone

Made from Fig. 12.25

Fruit fly embryonic CNS wild-type robo mutant comm mutant slit mutant (roundabout) (commissureless) (I faked this pic)

12.20 vertebrate interneurons

12.21 netrin knock out

12.10 locations within neural tube

Chapter 12: A special organ, The Nervous System Neurons and glia CNS and PNS sensory neurons, interneurons, motor neruons A series of developmental steps: proliferation, specification process elongation (axons and dendrites) “pathfinding” synaptogenesis

12.28 synaptogenesis 1

axon bundling during pathfinding creates nerves http://www.youtube.com/watch?v=EeunJ9j2Ckw

12.29 synaptogenesis 2

12.31 programmed cell death of neurons

12.32 synaptic refinement

Chapter 9: Reproduction The Saga of the Germ line cells Fertilization Sex determination Dosage compensation Fig. 9.19

9.6 germ cell migration

9.20 SRY on Y chromosome