mitochondrial myopathies By: Liliette rangel Period 5
How does mitochondrial Myopathy work? Mitochondrial Myopathy occurs when the mitochondria is unable to create enough energy for the body and therefore causes the person to feel lethargic and weak. The Mitochondria is the part of a cell that is in charge of creating energy or ATP from carbohydrates or fatty acids in the food we eat. Because the energy from the mitochondria are highly needed in nearly all the cells in the body, having a deficiency of it can affect tissues and organs as well.
What causes Mitochondrial myopathy? Mutation in genes Inherited from family “Myo” means muscle and “pathos” means disease
How It’s diagnosed An Exercise test is performed along with a neurological exam Check for Diabetes or problems in the liver or kidneys An EKG to check for cardiomyopathy MRI to check for brain abnormalities
Symptoms Neurological ad Muscular Problems Muscle weakness Exercise Intolerance Hearing Loss Trouble Balancing Seizures Learning Deficits
Treatments Though there is no real treatment or a cure, physical therapy can help with the symptoms along with Vitamin therapies. Change in Diet
Main Problems Low Energy Free Radicals Lactic Acidosis A chain reaction of an odd number of broken bonds within a molecule Lactic Acidosis An increase in in production of lactate
Possible syndromes Barth syndrome Kearns-Sayre syndrome Leigh syndrome Mitochondrial DNA depletion syndromes
Questions True or False. Mitochondrial Myopathy has no cure. Mitochondrial Myopathy occurs when the mitochondria does not produce enough… Vitamin C Whit blood cells Energy None of the above List 3 symptoms.
Bibliography "Mitochondrial Myopathy Fact Sheet." National Institutes of Health. U.S. Department of Health and Human Services, n.d. Web. 10 Dec. 2016. "Mitochondrial Myopathies (MM) | Muscular Dystrophy Association." Muscular Dystrophy Association. N.p., 18 Jan. 2016. Web. 10 Dec. 2016. "About Mitochondria Myopathy." Mitochondrial Myopathy Information Page. N.p., n.d. Web. 10 Dec. 2016.