Hairy cell leukemia. (Bone marrow core biopsy, 50 × Hairy cell leukemia. (Bone marrow core biopsy, 50 ×.) The specimen is completely infiltrated with neoplastic cells with generous cytoplasm. These cells often have a "fried egg" appearance and a loose infiltrating look in the marrow compartment. This is a classic bone marrow biopsy appearance in a patient with hairy cell leukemia associated with bone marrow failure and pancytopenia. (Used, with permission, from L Damon.) Source: Blood Disorders, Current Medical Diagnosis & Treatment 2017 Citation: Papadakis MA, McPhee SJ, Rabow MW. Current Medical Diagnosis & Treatment 2017; 2016 Available at: https://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/Books/1843/cmdt17_ch13_ef032.png&sec=135709133&BookID=1843&ChapterSecID=135708533&imagename= Accessed: October 30, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved