Volume 67, Issue 1, Pages (January 2016)

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Volume 67, Issue 1, Pages 71-79 (January 2016) Usefulness of atrial function for risk stratification in asymptomatic severe aortic stenosis Maria Chiara Todaro, MD, Scipione Carerj, MD, Bijoy Khandheria, MD, Maurizio Cusmà-Piccione, MD, PhD, Salvatore La Carrubba, MD, Francesco Antonini-Canterin, MD, Pietro Pugliatti, MD, PhD, Vitantonio Di Bello, MD, Giuseppe Oreto, MD, Gianluca Di Bella, MD, PhD, Concetta Zito, MD, PhD Journal of Cardiology Volume 67, Issue 1, Pages 71-79 (January 2016) DOI: 10.1016/j.jjcc.2015.04.010 Copyright © 2015 Japanese College of Cardiology Terms and Conditions

Fig. 1 Example of left atrial (LA) reservoir curves obtained by speckle tracking echocardiography in (A) a control subject without aortic stenosis (AS), (B) a patient with severe AS who remained asymptomatic during follow-up, and (C) a patient with severe AS who developed syncope after 8 months of follow-up. A significant peak's difference in these three LA reservoir curves is clearly evident. Journal of Cardiology 2016 67, 71-79DOI: (10.1016/j.jjcc.2015.04.010) Copyright © 2015 Japanese College of Cardiology Terms and Conditions

Fig. 2 Receiver operating characteristic (ROC) curves for left ventricular global longitudinal strain (LV GLS) (A), left atrial (LA) reservoir (B), and LA stiffness (C). A cut-off of ≥−16.8% [areas under the curve (AUC)=0.92; sensitivity=86%, specificity=80%] for LV GLS (A), of ≥19.8% (AUC=0.86, sensitivity=71%, specificity=84%) for LA reservoir (B), and of <0.78 (AUC=0.81, sensitivity 70%, specificity 89%) for LA stiffness (C), have the higher sensitivity and specificity for predicting events occurrence. Journal of Cardiology 2016 67, 71-79DOI: (10.1016/j.jjcc.2015.04.010) Copyright © 2015 Japanese College of Cardiology Terms and Conditions

Fig. 3 Kaplan–Meier curves according to left ventricular global longitudinal strain (LV GLS) (A), left atrial (LA) reservoir (B) and LA stiffness (C) identified cut-off values. Event-free survival is significantly better in patients with greater LV GLS (≥−16.8%, p<0.001), higher LA reservoir (≥19.8%, p=0.001), and lower LA stiffness (<0.78). Journal of Cardiology 2016 67, 71-79DOI: (10.1016/j.jjcc.2015.04.010) Copyright © 2015 Japanese College of Cardiology Terms and Conditions