Prevention of Knee Osteoarthritis in Overweight Females: The First Preventive Randomized Controlled Trial in Osteoarthritis Jos Runhaar, PhD, Marienke.

Slides:

Advertisements

Similar presentations

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.

Advertisements

Severe Tuberculosis Sepsis in an Immunocompetent Patient

Pneumothorax Recurrence Related to High-speed Lift

The Effect of Smoking on the Risk of Sciatica: A Meta-analysis

Sexuality The American Journal of Medicine

Shelley R. Salpeter, MD, FACP, Andrew J. Wall, MD, Nicholas S. Buckley

An Evidence-based Guide for Obesity Treatment in Primary Care

An Unusual Cause of Leg Ulcerations

Impact of More Restrictive Blood Transfusion Strategies on Clinical Outcomes: A Meta- analysis and Systematic Review Shelley R. Salpeter, MD, Jacob S.

A Pain in the Neck: Thyroid Abscess

An Evidence-based Guide for Obesity Treatment in Primary Care

Scientific and Organizational Collaboration in Comparative Effectiveness Research: The VA Cooperative Studies Program Model Grant D. Huang, MPH, PhD,

Maureen M. Okam, MD, MPH, Todd A. Koch, Minh-Ha Tran, DO

Systematic Review of Guidelines on Peripheral Artery Disease Screening

David R. Curran, MD, Terence K

Tim McAlindon, MD, MPH, Margaret Formica, MSPH, Christopher H

One Appendix, Two Different Pains

Systematic Review of the Mediterranean Diet for Long-Term Weight Loss

Systematic Review and Meta-analysis of Adverse Events of Low-dose Aspirin and Clopidogrel in Randomized Controlled Trials Kenneth R. McQuaid, MD, Loren.

A Randomized Controlled Trial of a Community-based Behavioral Counseling Program Craig A. Johnston, PhD, Stephanie Rost, MS, RD, Karen Miller-Kovach,

Gastric Diverticulum: A Rare Cause of Refractory Epigastric Pain

Nutritional, Physical, Cognitive, and Combination Interventions and Frailty Reversal Among Older Adults: A Randomized Controlled Trial Tze Pin Ng, MD,

Re-sprains during the first 3 months after initial ankle sprain are related to incomplete recovery: an observational study Marienke van Middelkoop, Rogier.

Overview of Current Learning Theories for Medical Educators

The Long-term Effectiveness of a Lifestyle Intervention in Severely Obese Individuals Jessica L. Unick, PhD, Daniel Beavers, PhD, Dale S. Bond, PhD, Jeanne.

Prevention of Knee Osteoarthritis in Overweight Females: The First Preventive Randomized Controlled Trial in Osteoarthritis Jos Runhaar, PhD, Marienke.

SAMe-TT2R2 Score, Time in Therapeutic Range, and Outcomes in Anticoagulated Patients with Atrial Fibrillation Pilar Gallego, MD, PhD, Vanessa Roldán,

Thomas E. MacMillan, MD, MSc, Terence Tang, MD, Rodrigo B

Diagnostic Accuracy of History Taking and Physical Examination for Assessing Anterior Cruciate Ligament Lesions of the Knee in Primary Care Harry P.

Epidemiology of Myelodysplastic Syndromes

A Randomized, Double-Blind, Placebo-Controlled Trial of Nutritional Supplementation During Acute Illness Salah Gariballa, MD, Sarah Forster, MSc, Stephen.

All-cause Mortality Associated with TNF-α Inhibitors in Rheumatoid Arthritis: A Meta- Analysis of Randomized Controlled Trials Lucile Poiroux, MD, Yannick.

Robert Goulden, MBBS, MSc, MPhil, MA The American Journal of Medicine

Peter M. Farrehi, MD, Kristen R. Clore, OTRL, J

Juice Plus or Toxicity Plus

Cupping Therapy-induced Iron Deficiency Anemia in a Healthy Man

The Reply The American Journal of Medicine

Jessica L. Lee, MD, MS, Esther S. Oh, MD, Rebecca W. Lee, MD, Thomas E

Assessment of FIBROSpect II to Detect Hepatic Fibrosis in Chronic Hepatitis C Patients Atif Zaman, MD, MPH, Hugo R. Rosen, MD, Ken Ingram, PA-C, Christopher.

Metabolic Syndrome and Sexual Function in Postmenopausal Women

The Recent History of Acupuncture

Effectiveness of glucosamine for symptoms of knee osteoarthritis: Results from an internet-based randomized double-blind controlled trial Timothy McAlindon,

Loop Diuretics for Heart Failure-associated Hyponatremia

Gout in African Americans

Shao-Hsien Liu, MPH, Jeffrey B. Driban, PhD, Charles B

Carlos Aguilar, MD, Valentin del Villar, MD

Repeated Hemoglobin A1C Ordering in the VA Health System

A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee

Insulin Order Sets Improve Glycemic Control and Processes of Care

The Reply The American Journal of Medicine

Does Methylphenidate Reduce the Symptoms of Chronic Fatigue Syndrome?

Stop Talking ‘Dirty’: Clinicians, Language, and Quality of Care for the Leading Cause of Preventable Death in the United States John F. Kelly, PhD, Sarah.

Seizure with Acute Pulmonary Infiltrates

Age Differences in Treatment and Control of Hypertension in US Physician Offices, : A Serial Cross-sectional Study Anna Gu, MD, PhD, Yu Yue,

Cluster Syncope The American Journal of Medicine

Effect of Folic Acid, with or without Other B Vitamins, on Cognitive Decline: Meta- Analysis of Randomized Trials David S. Wald, MA, MRCP, MD, Anuradhani.

Osteoarthritis and Cartilage

One-way Versus Two-way Text Messaging on Improving Medication Adherence: Meta- analysis of Randomized Trials David S. Wald, MD, FRCP, Shahena Butt, MSc,

Eagle's Syndrome The American Journal of Medicine

Ajay Major, MD, MBA, Mel Anderson, MD The American Journal of Medicine

Purple Urinary Bag Syndrome

A Post-cure Complication

Sister Mary Joseph's Node

Plasma Lactescence in Acute Pancreatitis

Trends in Prolonged Hospitalizations in the United States from 2001 to 2012: A Longitudinal Cohort Study Lauren Doctoroff, MD, Douglas J. Hsu, MD, Kenneth.

Acquired Generalized Lipodystrophy Following Immune Thrombocytopenia

Falls in Older Adults: Risk Assessment, Management and Prevention

Toward a More Responsible News Media

David Tian, MD, Ram Jhingan Mohan, MD, Gary Stallings, MD

Hypophosphatemia: Diagnostic Significance in Legionnaires’ Disease

Presentation transcript:

Prevention of Knee Osteoarthritis in Overweight Females: The First Preventive Randomized Controlled Trial in Osteoarthritis Jos Runhaar, PhD, Marienke van Middelkoop, PhD, Max Reijman, PhD, Sten Willemsen, PhD, Edwin H. Oei, PhD, MD, Dammis Vroegindeweij, PhD, MD, Gerjo van Osch, PhD, Bart Koes, PhD, Sita M.A. Bierma-Zeinstra, PhD The American Journal of Medicine Volume 128, Issue 8, Pages 888-895.e4 (August 2015) DOI: 10.1016/j.amjmed.2015.03.006 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure Flow-chart of participants in the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study. DEP = diet-and-exercise program. The American Journal of Medicine 2015 128, 888-895.e4DOI: (10.1016/j.amjmed.2015.03.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Appendix Figure 1 Mean quality of life (EuroQol) scores within randomized intervention groups. The American Journal of Medicine 2015 128, 888-895.e4DOI: (10.1016/j.amjmed.2015.03.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Appendix Figure 2 Mean WOMAC pain scores (range 0-100; higher scores mean more pain) within randomized intervention groups. The American Journal of Medicine 2015 128, 888-895.e4DOI: (10.1016/j.amjmed.2015.03.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Appendix Figure 3 Mean WOMAC function scores (range 0-100; higher scores mean less function) within randomized intervention groups. The American Journal of Medicine 2015 128, 888-895.e4DOI: (10.1016/j.amjmed.2015.03.006) Copyright © 2015 Elsevier Inc. Terms and Conditions

Appendix Figure 4 Actual weight loss (negative values represent weight gain from baseline) within randomized intervention groups. The American Journal of Medicine 2015 128, 888-895.e4DOI: (10.1016/j.amjmed.2015.03.006) Copyright © 2015 Elsevier Inc. Terms and Conditions