Myasthenia Gravis Johan Perrand Period 3

Overview Myasthenia gravis (MG) is referred to as a neuromuscular disorder that generates weakness in skeletal muscles, known as the muscles your body utilizes for movement. This impairment prevents crucial muscle contractions from occurring, resulting in muscle weakness.  Myasthenia Gravis is the primary disorder of neuromuscular transmission. It’s a considered a rare condition that affects between approximately 14 to 20 people out of 100,000 people inhabiting in the United States.

Causes Myasthenia Gravis is triggered by a malfunction in the transmission of nerve impulses to muscles. It happens to occur as normal communication between the nerve and muscle is intervened in the neuromuscular junction—which is the location at which the nerve cells attach with muscles they have dominance over.  As myasthenia gravis antibodies get in the way of the receptors for acetylcholine in the neuromuscular junction, it muscle contractions.

Symptoms The primary symptom of the Myasthenia Gravis Disease is weakness within voluntary skeletal muscles, which are the muscles that are in our control. Even though Myasthenia Gravis has a possibility of affecting a wide range of voluntary muscle, the muscles which control the eye and the eyelids movement, facial expression, and swallowing are affected. (The first noticeable symptom is weakness of the eye muscles.) The degree at which muscle weakness is involved in myasthenia gravis alters depending on the individuals.

Symptoms (cont.) Symptoms of Myasthenia Gravis involves: Difficulty communicating Conflicts moving around or carrying items Facial paralysis (Bells Palsy) Trouble breathing due to muscle weakness Swallowing or chewing becomes a task Fatigue Drooping of one eyelid Double Vision

Treatment No cure for Myasthenia Gravis has been discovered yet, however, there is a wide range of therapies available to aid in reducing and improving your muscle weakness. The objective of treatment is to handle symptoms and control the activity of your immune system. There are medications accessible to improve your muscle strength by restraining the reproduction of abnormal antibodies. The use of this medication has to be carefully monitored by your physician due to the fact they can cause severe side effects.

Complications Possibly a hazardous potential complication of Myasthenia Gravis is myasthenia crisis. It is composed of life-threatening muscle weakness that includes breathing problems out many other major issues.  Individuals that are diagnosed with Myasthenia Gravis have a higher risk of developing other autoimmune disorders such as lupus and rheumatoid arthritis. Death generally occurs as an outcome of the inability of respiratory muscles to function, known as respiratory failure.

Visuals on symptoms Dropping Facial Paralysis(Bell’s Palsy)

Statistics

Bibliography @healthline. "Myasthenia Gravis." Healthline. N.p., n.d. Web. 13 Dec. 2016. National Institutes of Health. U.S. Department of Health and Human Services, n.d. Web. 13 Dec. 2016. "Essentials of Human Anatomy & Physiology, 9th Edition." Essentials of Human Anatomy & Physiology, 9th Edition. N.p., n.d. Web. 13 Dec. 2016.

Question #1 Which of the following is an autoimmune disease EXCEPT? A. Rheumatoid Disease B. Myasthenia Disease C Lupus D. Alzheimer's Disease

Question #2 What is the first common noticed symptom by a myasthenia gravis patient? A. Breathing Difficulties B. Difficulty walking C. Weakness of the Eye Muscle D. None of the Above - Weakness of the eye muscle

Question #3 Myasthenia gravis is due to Acetylcholine receptors being blocked and destroyed by antibodies. A. True B. False -Acetylcholine