A preliminary investigation comparing pre–operative morphine and buprenorphine for postoperative analgesia and sedation in cats GW Stanway, BVSC, Cert.

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Presentation transcript:

A preliminary investigation comparing pre–operative morphine and buprenorphine for postoperative analgesia and sedation in cats GW Stanway, BVSC, Cert VA, PM Taylor, MA, Vet MB, PhD, DVA, Dip ECVA, DC Brodbelt, MA, Vet MB, DVA, Dip ECVA, MRCVS Veterinary Anaesthesia and Analgesia Volume 29, Issue 1, Pages 29-35 (January 2002) DOI: 10.1046/j.1467-2987.2001.00062.x Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 1 Pain score (0–100) in cats after acepromazine and either buprenorphine (stippled) (n = 18) or morphine (plain) (n = 14) pre–anaesthetic medication. Surgery performed after induction of anaesthesia with propofol during maintenance with halothane and nitrous oxide in oxygen. Pre: immediately before induction. Time: 30–420 minutes taken from the end of halothane administration. Plot shows median and interquartile range with extreme data points. *Significant difference between buprenorphine and morphine groups. Number marked for each group at time points = n. Veterinary Anaesthesia and Analgesia 2002 29, 29-35DOI: (10.1046/j.1467-2987.2001.00062.x) Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 2 Sedation score (0–100) in cats after acepromazine either buprenorphine (stippled) (n = 18) or morphine (plain) (n = 14) pre–anaesthetic medication. Surgery performed after induction of anaesthesia with propofol during maintenance with halothane and nitrous oxide in oxygen. Pre: immediately before induction. Time: 30–420 minutes taken from the end of halothane administration. Plot shows median and interquartile range with extreme data points. No significant differences between buprenorphine and morphine groups. Number marked for each group at time points = n. Veterinary Anaesthesia and Analgesia 2002 29, 29-35DOI: (10.1046/j.1467-2987.2001.00062.x) Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 3 Postoperative heart rate (beats minute−1, mean ± SD) in cats after acepromazine and either buprenorphine (dotted line) (n = 18) or morphine (plain line) (n = 14) pre–anaesthetic medication. Surgery performed after induction of anaesthesia with propofol during maintenance with halothane and nitrous oxide in oxygen. Time: 30–420 minutes taken from the end of halothane administration. *Significant difference between buprenorphine and morphine groups. Number marked for each group at time points = n. Veterinary Anaesthesia and Analgesia 2002 29, 29-35DOI: (10.1046/j.1467-2987.2001.00062.x) Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure 4 Postoperative respiratory rate (breath minute−1 mean ± SD) in cats after acepromazine and either buprenorphine (dotted line) (n = 18) or morphine (plain line) (n = 14) pre–anaesthetic medication. Surgery performed after induction of anaesthesia with propofol during maintenance with halothane and nitrous oxide in oxygen. Time: 30–420 minutes taken from the end of halothane administration. No significant difference between buprenorphine and morphine groups. Number marked for each group at time points = n. Veterinary Anaesthesia and Analgesia 2002 29, 29-35DOI: (10.1046/j.1467-2987.2001.00062.x) Copyright © 2002 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions