Plasma drug concentration-time profiles after IV infusion

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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.
Presentation transcript:

Plasma drug concentration-time profiles after IV infusion Plasma drug concentration-time profiles after IV infusion. IV infusion is stopped at steady state (A) or prior to steady state (B). In both cases, plasma drug concentrations decline exponentially (first order) according to a similar slope. Source: Intravenous Infusion, Applied Biopharmaceutics & Pharmacokinetics, 7e Citation: Shargel L, Yu AC. Applied Biopharmaceutics & Pharmacokinetics, 7e; 2016 Available at: http://accesspharmacy.mhmedical.com/DownloadImage.aspx?image=/data/books/1592/sha_ch6_f002.png&sec=100670253&BookID=1592&ChapterSecID=100670238&imagename= Accessed: October 30, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved

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