Fig. 4. Effect of curcumin on urine SOD and MDA, Nrf2/Keap1, and HO-1 protein expression in the urine or renal cortex. (A) Urinary SOD was significantly.

Slides:

Advertisements

Similar presentations

Date of download: 9/17/2016 Copyright © 2016 American Society of Anesthesiologists. All rights reserved. Fig. 3. Activities of superoxide dismutase, catalase,

Advertisements

Date of download: 9/17/2016 Copyright © 2016 American Society of Anesthesiologists. All rights reserved. Fig. 4. Activities of superoxide dismutase (A.

FIG. 1. H2S contents in plasma and myocardial tissue were measured by the Methylene Blue method (A, B). Representative immunoblots and densitometric.

Invest. Ophthalmol. Vis. Sci ;44(5): doi: /iovs Figure Legend:

Supplementation of vitamin E, selenium and increased energy allowance mitigates the transition stress and improves postpartum reproductive performance.

Curcumin could ameliorate diabetic vascular inflammation

OXIDATIVE STRESS IN PATIENTS WITH ACUTE STROKE AND IT’S EFFECT ON RENAL FUNCTION Dr Monem Makki Alshok Dr Moayed F. Al-Gazally Dr Ali Hasson Hussain.

Volume 35, Issue 6, Pages (June 2015)

Fig. 2. Effects of Ang II on the p130Cas protein assayed by Western blotting. (A) The bands for p130Cas protein at 130 kDa are reduced by 10-7 M Ang II.

Diabetic Cardiovascular Disease Predicts Chronic Kidney Disease Awareness in the Kidney Early Evaluation Program Cardiorenal Med 2011;1:45–52 - DOI: /

Α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage Cell Physiol Biochem.

Selenium-deficient diet induces renal oxidative stress and injury via TGF-β1 in normal and diabetic rats Alluru S. Reddi, Jaya S. Bollineni Kidney International

Fig. 2. Effect of curcumin on urine albumin levels and 24-hour albumin/creatinine ratio (ACR). (A) At 45 weeks of age, urinary albumin levels of the CUR.

Administration of Curcumin Protects Kidney Tubules Against Renal Ischemia-Reperfusion Injury (RIRI) by Modulating Nitric Oxide (NO) Signaling Pathway Cell.

Background and Objectives:

Loss of renal function and microvascular blood flow after suprarenal aortic clamping and reperfusion (SPACR) above the superior mesenteric artery is greatly.

Mike L. Green, Robert W. Freel, Marguerite Hatch Kidney International

Volume 85, Issue 3, Pages (March 2014)

Carmen Peralta, Mónica B. Jiménez-Castro, Jordi Gracia-Sancho

Oxidative stress mediates hippocampal neuron death in rats after lithium–pilocarpine- induced status epilepticus Jinzhi Liu, Aihua Wang, Lili Li, Yanfei.

Critical Role of 5-Lipoxygenase and Heme Oxygenase-1 in Wound Healing

Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration.

Volume 76, Issue 8, Pages (October 2009)

Volume 69, Issue 9, Pages (May 2006)

A 43kD protein from the herb, Cajanus indicus L

Caffeine plus nicotine improves motor function, spatial and non-spatial working memory and functional indices in BALB/c male mice P.A. Adeniyi, E.P.

Mary Chatterjee, Kasturi Sarkar, Parames C. Sil Pathophysiology

Inhibition of cytochrome P450 2E1 and activation of transcription factor Nrf2 are renoprotective in myoglobinuric acute kidney injury Zhe Wang, Sudhir.

Volume 135, Issue 6, Pages e2 (December 2008)

Hyperketonemia (ketosis), oxidative stress and type 1 diabetes

Parenteral iron nephrotoxicity: Potential mechanisms and consequences1

Iodinated contrast induced renal vasoconstriction is due in part to the downregulation of renal cortical and medullary nitric oxide synthesis Stuart.

Volume 78, Issue 9, Pages (November 2010)

INT-767 treatment prevents the increase in renal HIF and Glut1 expression and ER stress in diabetic DBA/2J mice. INT-767 treatment prevents the increase.

Volume 63, Issue 4, Pages (April 2003)

A. Jimoh, Y. Tanko, A. Ahmed, A. Mohammed, J.O. Ayo Pathophysiology

Hua Liu, Steven A. Bigler, Jeffrey R. Henegar, Radhakrishna Baliga

Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease Stacey Ruiz, Pablo E. Pergola, Richard.

Mohamed Ahmed Abd-Elmoaty, Ph. D. , Ramadan Saleh, M. D

Volume 66, Issue 5, Pages (November 2004)

Trimetazidine reduces early and long-term effects of experimental renal warm ischemia: A dose effect study Jerome Cau, MD, Frederic Favreau, PhD, Jean.

Volume 79, Issue 5, Pages (March 2011)

Stuart I. Myers, MD, Li Wang, BS, Fang Liu, BS, Lori L. Bartula, BS

Volume 59, Issue 5, Pages (May 2001)

Carmen Peralta, Mónica B. Jiménez-Castro, Jordi Gracia-Sancho

Volume 79, Issue 1, Pages (January 2011)

PPARα agonist fenofibrate improves diabetic nephropathy in db/db mice

Volume 3, Issue 4, Pages (October 2014)

Volume 87, Issue 2, Pages (February 2015)

Sanjeev Noel, Abdel R.A. Hamad, Hamid Rabb Kidney International

Volume 70, Issue 3, Pages (August 2006)

Volume 68, Issue 6, Pages (December 2005)

Juliana Saraiva Anjos, MD, Ludmila F. M. F

Volume 72, Issue 12, Pages (December 2007)

Volume 70, Issue 10, Pages (November 2006)

Volume 72, Issue 8, Pages (October 2007)

Volume 71, Issue 9, Pages (May 2007)

Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis H.-C. Yang, L.-J. Ma, J. Ma, A.B. Fogo

Mahesh Mysore Shivananjappa, Muralidhara

Volume 63, Issue 1, Pages (January 2003)

Nosratola D. Vaziri, Fariba Oveisi, Yaoxian Ding Kidney International

Endothelin antagonists in renal disease

Isyaku U. Yarube, Joseph O. Ayo, Rabiu A. Magaji, Isma’il A. Umar

Loss of renal function and microvascular blood flow after suprarenal aortic clamping and reperfusion (SPACR) above the superior mesenteric artery is greatly.

Iodinated contrast induced renal vasoconstriction is due in part to the downregulation of renal cortical and medullary nitric oxide synthesis Stuart.

Nrf2−/− mice suffered greater renal damage by STZ compared with Nrf2+/+ mice. Nrf2−/− mice suffered greater renal damage by STZ compared with Nrf2+/+ mice.

Jens Gaedeke, Nancy A. Noble, Wayne A. Border Kidney International

Volume 74, Issue 8, Pages (October 2008)

* * * ** ** ** ** ** ** Fig. 1..

Eric N Haugen, Anthony J Croatt, Karl A. Nath Kidney International

Presentation transcript:

Fig. 4. Effect of curcumin on urine SOD and MDA, Nrf2/Keap1, and HO-1 protein expression in the urine or renal cortex. (A) Urinary SOD was significantly increased in the CUR group, compared to the DM group, at 45 weeks of age. (B) Urinary MDA significantly decreased in the CUR group, compared with the DM group. (C) Representative pictures of Nrf2/Keap1 protein ratio and HO-1 expression in renal kidney cortex of 45 weeks of age. (D) Reduced Nrf2/Keap1 protein ratio and HO-1 protein expression related to renal oxidative stress, which were significantly increased in the CUR group. Data expressed as mean±SD. *p<0.05 vs. CON, †p<0.05 vs. DM. CON, control group; DM, diabetic group; CUR, curcumin-treated (100 mg/kg, p.o.) diabetic group; SOD, superoxide dismutase; MDA, malondialdehyde; Nrf2, nuclear factor (erythroid-derived 2)-like 2; HO-1, heme oxygenase-1. Fig. 4. Effect of curcumin on urine SOD and MDA, Nrf2/Keap1, and HO-1 protein expression in the urine or renal cortex. (A) Urinary SOD was significantly increased in the CUR group, compared to the DM group, at 45 weeks of age. (B) Urinary MDA significantly decreased in the CUR group, compared with the DM group. (C) Representative pictures of Nrf2/Keap1 protein ratio. . . Yonsei Med J. 2016 May;57(3):664-673. http://dx.doi.org/10.3349/ymj.2016.57.3.664