Why is blood so important to survival?

Bleeding Stories Anyone?

Why is blood so important to survival?

Functions of Blood transport medium protection (immunity) regulation

What is blood made of?

What are the four main parts of blood? Red blood cells White blood cells Platelets Plasma

(as a cell, tissue, organ, or organ system?) How would blood be classified? (as a cell, tissue, organ, or organ system?)

blood - a fluid tissue composed of plasma in which RBC's, WBC's, and platelets are suspended

Red Blood Cells

There are 5,000,000 red blood cells in one drop (1 microliter) of blood There are about 5 liters of blood in the body. How many red blood cells are there in the body?

There are 25,000,000,000,000 red blood cells in the human body. If 3 million red blood cells die each second, then how many must be made to replace them in one day? 259,200,000,000

Development of Red Blood cells

Bone Marrow

Why do red blood cells have this shape?

Side view of a red blood cell oxygen carbon dioxide (blood vessel in lungs)

Side view of a red blood cell oxygen carbon dioxide (blood vessel in tissues)

How is a red blood cell like a taxi? oxygen Tissues Lungs Carbon dioxide

1 2 1 - Oxygen, nutrients, hormones CELLS IN BODY BLOOD 1 – metabolic wastes including Carbon dioxide, hormones

red blood cell

Hemoglobin

Hemoglobin a complex iron-containing protein that carries oxygen and carbon dioxide throughout the body and gives blood its red color

Sickled Cell

Anemia Decreased ability of the red blood cells to provide adequate oxygen supplies to body tissues.

Sickle-cell anemia: an inherited, potentially lethal disease in which a defect in hemoglobin, the oxygen-carrying pigment in the blood, causes distortion (sickling) and loss of red blood cells, producing damage to organs throughout the body.

Causes of Anemia abnormal hemoglobin insufficient amount of hemoglobin insufficient amount of red blood cells Causes - dietary deficiency - premature destruction of red blood cells

White Blood Cells

Immune Cells

White Blood Cells protect the body from pathogens

phagocytosis http://www.youtube.com/watch?v=fpOxgAU5fFQ http://www.sp.uconn.edu/~terry/Common/phago053.html

Centrifuge

Plasma clear straw-colored liquid portion of the blood 90% water 10% dissolved substances Glucose, Salts, Amino Acids, Fatty Acids, Vitamins, Enzymes, Hormones, Cellular Wastes, Proteins

Regulate blood clotting Plasma Proteins Albumin Prevents water from leaving blood and entering cells Clotting Factors Regulate blood clotting Globulins Transporters, Antibodies

Concept Map Wordbank Water Hemoglobin Platelets White Blood Cells Anemia Clotting factors Immunity Oxygen Carbon Dioxide Blood Clotting Plasma Red Blood Cells

Blood Cells Cell Fragments 1. _____ 2. _____ 3. ______ 5. ______ Directions: Use the word bank on the following page and the pages in your text to fill in the missing words. Blood contains Cells Cell Fragments 1. _____ is mostly also contains such as called 2. _____ 3. ______ 5. ______ 6. ________ 4. ______ contain too few causes functions in 7. ___________ needed for 9. _________ 8. ______ 10. ____________ which carries 11. ______ 12. _________

Blood Cells Cell Fragments 1. Plasma 2. RBCs 3. WBCs 5. Water 6. Clotting factors 4. Platelets 7. hemoglobin 9. immunity 8. anemia 10. Blood clotting 11. oxygen 12. Carbon dioxide

What is this?

How do blood clots form?

Clotting Animation http://health.howstuffworks.com/adam-200077.htm http://www.youtube.com/watch?v=--bZUeb83uU http://www.youtube.com/watch?v=xNZEERMSeyM http://www.youtube.com/watch?v=vEmsaXA-go0 http://health.howstuffworks.com/adam-200077.htm https://www.lifehouseproductions.com/Clotting.html

Platelets

Platelets Adhere (attach) to the walls of broken blood vessels (sealant) Adhere to each other to help establish a clot Release chemicals which stimulate the blood to clot

A Blood Clot Forming 1 platelet 2 fibrin 3 Red blood cell

The Process of Blood Clotting Blood vessel injured Platelets release Thromboplastin Prothrombin Thrombin Fibrinogen Fibrin Fibrin Net traps Platelets and Red Blood cell to form clot

The Process of Blood Clotting When a blood vessel is injured, platelets in the blood release a protein (fibrin) that forms a net This net traps blood cells and platelets forming a blood clot

Coronary Thrombosis

How are blood clots dissolved?

What do these creatures have in common?

substances that prevent clot formation anticoagulants substances that prevent clot formation - heparin - used as a drug after surgery to prevent clotting

Imagine that you could create an ideal artificial blood Imagine that you could create an ideal artificial blood. Describe some of the characteristics you would want it to have.

Blood pH 7.35 to 7.45!!!

CO2 + H2O H2CO3 Carbonic acid H+ + HCO3- Bicarbonate ion Carbonic anhydrase H2CO3 Carbonic acid H+ + HCO3- Bicarbonate ion In lungs In tissues