Specificity and predictive value of circulating testosterone assessed by tandem mass spectrometry for the diagnosis of polycystic ovary syndrome by the.

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Presentation transcript:

Specificity and predictive value of circulating testosterone assessed by tandem mass spectrometry for the diagnosis of polycystic ovary syndrome by the National Institutes of Health 1990 criteria Wael A. Salameh, M.D., Mildred M. Redor-Goldman, B.S., Nigel J. Clarke, Ph.D., Ruchi Mathur, M.D., Ricardo Azziz, M.D., Richard E. Reitz, M.D. Fertility and Sterility Volume 101, Issue 4, Pages 1135-1141.e2 (April 2014) DOI: 10.1016/j.fertnstert.2013.12.056 Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Figure 1 ROC curve for detecting PCOS using TT measured by LC-MS/MS or RIA (A), FT measured by LC-MS/MS or RIA (B), or both TT and FT (C). Fertility and Sterility 2014 101, 1135-1141.e2DOI: (10.1016/j.fertnstert.2013.12.056) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 1 Deming regression of LC-MS/MS versus RIA for TT (panel A) and FT (panel B). Fertility and Sterility 2014 101, 1135-1141.e2DOI: (10.1016/j.fertnstert.2013.12.056) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Supplemental Figure 2 Distribution of individual subject results for TT (panel A) and FT (panel B). Note that while there is a similar distribution for PCOS and control women for TT measured by LC-MS/MS and RIA, values for both groups are generally higher for RIA than for LC-MS/MS. Fertility and Sterility 2014 101, 1135-1141.e2DOI: (10.1016/j.fertnstert.2013.12.056) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions