MRI findings in MS. A. Axial first-echo image from T2-weighted sequence demonstrates multiple bright signal abnormalities in white matter, typical for.

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Arcot Chandrasekhar, M.D. Ashok Kumar, M.D. November 5, 2013

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MRI findings in MS. A. Axial first-echo image from T2-weighted sequence demonstrates multiple bright signal abnormalities in white matter, typical for MS. B. Sagittal T2-weighted FLAIR (fluid attenuated inversion recovery) image in which the high signal of CSF has been suppressed. CSF appears dark, while areas of brain edema or demyelination appear high in signal as shown here in the corpus callosum (arrows). Lesions in the anterior corpus callosum are frequent in MS and rare in vascular disease. C. Sagittal T2-weighted fast spin echo image of the thoracic spine demonstrates a fusiform high-signal-intensity lesion in the midthoracic spinal cord. D. Sagittal T1-weighted image obtained after the intravenous administration of gadolinium DTPA reveals focal areas of blood-brain barrier disruption, identified as high-signal-intensity regions (arrows). Source: Chapter 380. Multiple Sclerosis and Other Demyelinating Diseases, Harrison's Principles of Internal Medicine, 18e Citation: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. Harrison's Principles of Internal Medicine, 18e; 2012 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/harr/harr_c380f003d.jpg&sec=40764992&BookID=331&ChapterSecID=40727196&imagename= Accessed: November 01, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved