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Copyright © 2000 American Medical Association. All rights reserved. From: Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma Arch Ophthalmol. 2000;118(3):378-384. doi:10.1001/archopht.118.3.378 Figure Legend: Low-power microphotographs of coronal sections of the left lateral geniculate nucleus (LGN) from control (left) and glaucomatous (right) monkeys, immunostained for parvalbumin. All 6 layers in the control are strongly immunoreactive for parvalbumin as indicated by numbers. There is overall shrinkage of the LGN and a decrease in immunoreactivity in parvocellular layers 4 and 6 in the glaucomatous LGN compared with the control. The bar indicates 0.5 mm. Date of download: 11/2/2017 Copyright © 2000 American Medical Association. All rights reserved.

Copyright © 2000 American Medical Association. All rights reserved. From: Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma Arch Ophthalmol. 2000;118(3):378-384. doi:10.1001/archopht.118.3.378 Figure Legend: High-power microphotographs of lateral geniculate nucleus (LGN) coronal sections show parvalbumin-immunoreactive neurons in layer 6 of control (top) and glaucomatous (bottom) monkeys. In the controls, the darkly stained cell bodies are plump and numerous; in the glaucomatous monkeys, they are shrunken and few. The bar indicates 50 µm. Date of download: 11/2/2017 Copyright © 2000 American Medical Association. All rights reserved.

Copyright © 2000 American Medical Association. All rights reserved. From: Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma Arch Ophthalmol. 2000;118(3):378-384. doi:10.1001/archopht.118.3.378 Figure Legend: Top, Mean number of parvalbumin-immunoreactive neurons in left lateral geniculate nucleus (LGN) magnocellular layer 1 connected to the right eye of control or glaucomatous monkeys. Error bars indicate SDs. The asterisk indicates that the mean number of neurons was significantly reduced by 45% in glaucomatous monkeys (P =.02). Bottom, The number of parvalbumin-immunoreactive neurons in the left LGN magnocellular layer 1 for the 4 glaucomatous monkeys with varying percentage of optic nerve fiber loss. The horizontal solid line indicates the mean number of parvalbumin-immunoreactive neurons in the left LGN magnocellular layer 1 for the control monkeys (n = 5). The horizontal dotted line indicates the mean number of neurons minus 2 SDs for control monkeys. Date of download: 11/2/2017 Copyright © 2000 American Medical Association. All rights reserved.

Copyright © 2000 American Medical Association. All rights reserved. From: Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma Arch Ophthalmol. 2000;118(3):378-384. doi:10.1001/archopht.118.3.378 Figure Legend: Top, Mean number of parvalbumin-immunoreactive neurons in left lateral geniculate nucleus (LGN) parvocellular layers 4 and 6 connected to the right eye of control or glaucomatous monkeys. Error bars indicate SDs. The asterisk indicates that the mean number of neurons was significantly reduced by 42% in glaucomatous monkeys (P =.03). Bottom, The number of parvalbumin-immunoreactive neurons in the left LGN parvocellular layers 4 and 6 for the 4 glaucomatous monkeys with varying percentage of optic nerve fiber loss. The horizontal solid line indicates the mean number of parvalbumin-immunoreactive neurons in the left LGN parvocellular layers 4 and 6 for the control monkeys (n = 5). The horizontal dotted line indicates the mean number of neurons minus 2 SDs for the control monkeys. Date of download: 11/2/2017 Copyright © 2000 American Medical Association. All rights reserved.