From: Reversible Binding of Kynurenine to Lens Proteins: Potential Protection by Glutathione in Young Lenses Invest. Ophthalmol. Vis. Sci.. 2007;48(8):3705-3713.

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From: Reversible Binding of Kynurenine to Lens Proteins: Potential Protection by Glutathione in Young Lenses Invest. Ophthalmol. Vis. Sci.. 2007;48(8):3705-3713. doi:10.1167/iovs.06-1061 Figure Legend: Deamination of Kyn at pH 7.0 and reaction with lens proteins to form Kyn-amino acid adducts. Protein-bound Kyn-His is stable under physiological conditions, but both Kyn-Cys and Kyn-Lys are unstable. Glutathione reacts with deaminated Kyn and also enhances the rate of decomposition of Kyn-Cys. Date of download: 11/2/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.