Tuberculid A tuberculid is a cutaneous immunological reaction to the presence of occult TB in a patient with moderate to high immunity. The main features.

Slides:



Advertisements
Similar presentations
TUBERCULOSIS.
Advertisements

Nodules and infiltrates
Tuberculous adenopathies
TUBERCULOSIS in Children Gatmaitan, Raymond Golpeo, Kirsten Hemedes, Marielisse.
Pathology of TB: 1 "It is nice to have money and the things that money can buy, but it's important to make sure you haven't lost the things money can't.
BY Dr Abiodun Mark Akanmode.. Identify the slide.
Diagnosing Tuberculosis in Children
Senile purpura: Multiple purpuric macules Idiopathic thrombocytopenic purpura: Multiple petechiae on the arm.
 Pulmonary Tuberculosis BY: MOHAMED HUSSEIN. Cause  Caused by Mycobacterium tuberculosis (M. tuberculosis)  Gram (+) rod (bacilli). Acid-fast  Pulmonary.
PHTHISIOLOGY.
Pathology of TB: 1 "It is nice to have money and the things that money can buy, but it's important to make sure you haven't lost the things money can't.
1 Tuberculosis: Basics Rick Speare Anton Breinl Centre School of Public Health, Tropical Medicine and Rehabilitation Sciences James Cook University 16.
Granulomatous diseases Dr Shaesta Naseem
Revision respiratory practical block. A closer view of the lobar pneumonia demonstrates the distinct difference between the upper lobe and the consolidated.
SALIENT FEATURE Mr. Sharif, aged 40 Years, hailed from Mymensingh Jail, came to MMCH on with the complaints of: 1. One rough surfaced elevation.
The pathogenesis of Tuberculosis
Mycobacterial Infections Dr Qassim S. Al- Chalabi.
Cutaneous Tuberculosis Dr. (Prof.) Archana Singal University College of Medical Sciences & GTB Hospital, New Delhi Digital Lecture Series : Chapter 09.
Intraocular Tuberculosis
Iris Granuloma Dr Mamta Agarwal Dr J Biswas. History 44yr / M 44yr / M C/O mild redness, decreased vision & mass C/O mild redness, decreased vision &
Disease Detectives Refer to CDC.gov for answers. Disease One.
PRACTICAL 4 Foundation Block Pathology Dept, KSU.
IV.CHRONIC INTERSTITIAL (RESTRICTIVE, INFILTRATIVE) LUNG DISEASES 1.
Bacterial skin infections. The skin provides a remarkably good barrier against bacterial infections. Although many bacteria come in contact with or reside.
PRIMARY PULMONARY TB Clinical Features: (in children) No symptoms or signs and passes unnoticed in the majority of cases  characterized by 1ry lesion.
PANNICULITIS Gentleman’s Review Daniel Martingano OMSII.
Granulomatous Diseases PRACTICAL Foundation Block 2015 Pathology Dept, KSU.
Sarcoidosis.
Sarcoidosis. SARCOIDOSIS  Definition: Idiopathic systemic disorder characterized by accumulation of lymphocytes and monocytes in many organs forming.
-Dr Sowmya Srinivas. INTRODUCTION  When circulating blood reaches the capillaries, part of its fluid content passes into the surrounding tissues as tissue.
Tuberculosis of the Skin
Tuberculosis.
بسم الله الرحمن الرحيم.
Mycobacterial Infections
Management of the Newborn When Maternal TB Suspected
Granulomatous inflammation
Medullary Thyroid Carcinoma
LEPROSY CUTANEOUS TUBERCULOSIS SARCOIDOSIS
Mycobacterial diseases Tuberculosis
This is an archived document.
Tuberculosis of intrathoracic lymph nodes
Inflammation Case Presentation
Sarcoidosis Dr.Kassim.sultan F.R.C.P.
Seyhan I. Celikoglu, M.D., Louis Siltzbach, M.D., F.C.C.P. 
Tuberculosis By: Shefaa’ Q’aqa’.
Dr Dawood Quiz questions.
Dr. Meg-angela Christi Amores
Refractory cutaneous lichenoid sarcoidosis treated with tranilast
India Prof. Dr. Jyotirmay Biswas MS. FMRF, FNAMS, FIC Path., FAICO
Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Diagnosing Intrathoracic Tuberculosis  Jiayuan Sun, MD, PhD, Jiajun Teng, MD, Huizhen.
SARCOIDOSIS Idiopathic multisystem disorder
بسم الله الرحمن الرحيم.
A 30 year old man with headaches, imbalance and aphasia
Etiologic link between sarcoidosis and Propionibacterium acnes
Apixaban Causing Leukocytoclastic Vasculitis
Khalid Al Hawsawi Dermatology Consultant
Which is true about a tuberculin skin test (TST):
Nonphoto-exposed initial cutaneous manifestation of lupus after zoster: A case of Wolf's isotopic reaction  Molly Storer, MS, Rosalynn M. Nazarian, MD,
Volume 149, Issue 5, Pages e133-e136 (May 2016)
CLINICAL FEATURES OF NEOPLASIA
Down the Rabbit Hole: Cutaneous Tuberculosis
Here is chronic endometritis with lymphocytes and plasma cells in the endometrial stroma. In general, the inflammatory infiltrate of chronic inflammation.
Cutaneous Manifestations of Chronic Graft-versus-Host Disease
Volume 1, Issue 6, Pages (November 2015)
Pityriasis rubra pilaris with histologic features of lichen nitidus
Volume 4, Issue 4, Pages (May 2018)
Diseases of the Respiratory System Pathology of tuberculosis
Quiz page answers January 2005
Definition, Mechanism and Causes of Granulomas
Volume 5, Issue 9, Pages (September 2019)
Presentation transcript:

Tuberculid A tuberculid is a cutaneous immunological reaction to the presence of occult TB in a patient with moderate to high immunity. The main features of tuberculid are the absence of organism in smears and negative mycobacterial culture, positive tuberculin test and rapid resolution of the lesions with antitubercular therapy. Based on the detection of M. tuberculosis DNA by polymerase chain reaction (PCR), only lichen scrofulosorum (LS) may be considered to be true tuberculid, as PCR positivity has been observed in other tuberculids, i.e. papulonecrotic tuberculid and erythema induratum

Erythematous, scaly and grouped lesions of lichen scrofulosorum over the back

lichen scrofulosorum Grouped or clustered follicular papules, most commonly present on the trunk Commnly misdiagnosis as some other follicular disorder such as keratosis pilaris, lichen spinulosus, pityriasis rubra pilaris or lichen nitidus The second most common pattern of cutaneous TB in children A systemic focus of TB is detected in a majority of LS cases (72%) , the most common being involvement of lymph nodes (cervical, mediastinal or hilar)

lichen scrofulosorum Bx: superficial perifollicular epithelioid granulomas without any caseation AFB are not detected, mycobacterial cultures are negative from lesional biopsies and PCR is also negative

Papulonecrotic tuberculids Symmetrically distributed firm and dusky red necrotizing papules present predominantly over the extremities that heal with varioliform scarring Histology shows wedge-shaped necrosis with nonspecific perivascular infiltrates or tubercular granulomas surrounding the necrosis with  leukocytoclastic vasculitis M. tuberculosis DNA is frequently detected by PCR

Erythema induratum of Bazin Association with pulmonary TB is frequent lobular panniculits with vasculitis and Mantoux test is strongly positive M. tuberculosis DNA is detected by PCR in more than 50% of the cases