Stem Cell Engraftment and Survival in the Ischemic Heart

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Presentation transcript:

Stem Cell Engraftment and Survival in the Ischemic Heart Kai Hong Wu, MD, Xu Ming Mo, MD, Zhong Chao Han, MD, PhD, Bin Zhou, PhD The Annals of Thoracic Surgery Volume 92, Issue 5, Pages 1917-1925 (November 2011) DOI: 10.1016/j.athoracsur.2011.07.012 Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Factors affecting cell engraftment and strategies to improve cell engraftment and survival. Cell apoptosis and death, mechanical loss, and cell escape from the site of transplantation are the major factors in a low rate of cell engraftment and survival in the ischemic heart. Inhibition of apoptosis or promotion of cell survival by preconditioning, genetic modification, microencapsulation, magnetic targeting, and myocardial tissue engineering have been attempted to improve cell engraftment and subsequent recovery of cardiac function. The Annals of Thoracic Surgery 2011 92, 1917-1925DOI: (10.1016/j.athoracsur.2011.07.012) Copyright © 2011 The Society of Thoracic Surgeons Terms and Conditions