From: VEGF: From Discovery to Therapy: The Champalimaud Award Lecture

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Date of download: 5/27/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Correlation of Increased Vascular Endothelial Growth.

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From: VEGF: From Discovery to Therapy: The Champalimaud Award Lecture Trans. Vis. Sci. Tech.. 2016;5(2):9. doi:10.1167/tvst.5.2.9 Figure Legend: Experimental iris neovascularization. (A) Fundus photograph immediately following laser vein occlusion. (B) Color photograph showing new vessels on the surface of the iris, which appear 4 to 7 days after laser vein occlusion. (C) Fluorescein angiography showing iris neovascularization with abundant leakage of fluorescein (grade 3). (D) Fundus photograph immediately following sham laser, aimed adjacent to the retinal vessels and producing retinal injury but preserving normal vasculature. (E) Color photograph of iris 12 days after sham laser, which appears normal. (F) Fluorescein angiography of the iris in (E), showing normal iris vessels with no fluorescein leakage (grade 0). Reproduced with permission from Miller JW, Adamis AP, Shima DT, et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogensis in a primate model. Am J Pathol. 1994;145:574–584. Copyright 1994 Elsevier.17 Date of download: 11/3/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.