Effects of cancer treatment on ovarian function Jaymeson S. Stroud, M.D., David Mutch, M.D., Janet Rader, M.D., Matt Powell, M.D., Premal H. Thaker, M.D., Perry W. Grigsby, M.D.  Fertility and Sterility  Volume 92, Issue 2, Pages 417-427 (August 2009) DOI: 10.1016/j.fertnstert.2008.07.1714 Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 1 The solution of the Faddy-Gosden differential equation for the primordial follicle population from birth to menopause. (A) At birth, 701,000 follicles. (B) Accelerated decline at age 38 years, 25,000 follicles. (C) At menopause, 1,000 follicles. (From Wallace and Kelsey [4]. Reprinted by permission of the publisher.) Fertility and Sterility 2009 92, 417-427DOI: (10.1016/j.fertnstert.2008.07.1714) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 2 (a) Model for predicting ovarian failure after radiotherapy—example case and (b) with confidence intervals included. (From Wallace et al. [7]. Reprinted by permission of the publisher.) Fertility and Sterility 2009 92, 417-427DOI: (10.1016/j.fertnstert.2008.07.1714) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

Figure 3 The effective (red, upper) and mean (blue, lower) sterilizing dose of radiation for a given treatment age. (From Wallace et al. [7]. Reprinted by permission of the publisher.) Fertility and Sterility 2009 92, 417-427DOI: (10.1016/j.fertnstert.2008.07.1714) Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions