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Copyright © 2012 American Medical Association. All rights reserved. From: Efficacy of Omega-3 Fatty Acid Supplements (Eicosapentaenoic Acid and Docosahexaenoic Acid) in the Secondary Prevention of Cardiovascular DiseaseA Meta-analysis of Randomized, Double-blind, Placebo-Controlled Trials Arch Intern Med. 2012;172(9):686-694. doi:10.1001/archinternmed.2012.262 Figure Legend: Figure 1. Identification of relevant randomized, double-blind, placebo-controlled trials. Date of download: 11/3/2017 Copyright © 2012 American Medical Association. All rights reserved.

Copyright © 2012 American Medical Association. All rights reserved. From: Efficacy of Omega-3 Fatty Acid Supplements (Eicosapentaenoic Acid and Docosahexaenoic Acid) in the Secondary Prevention of Cardiovascular DiseaseA Meta-analysis of Randomized, Double-blind, Placebo-Controlled Trials Arch Intern Med. 2012;172(9):686-694. doi:10.1001/archinternmed.2012.262 Figure Legend: Figure 2. Begg funnel plot and Egger test P value for identifying publication bias in a meta-analysis of 13 trials. RR indicates relative risk. Because the study by Garbagnati et al resulted in a zero outcome, it was excluded in funnel plot analysis by the STATA program. Date of download: 11/3/2017 Copyright © 2012 American Medical Association. All rights reserved.

Copyright © 2012 American Medical Association. All rights reserved. From: Efficacy of Omega-3 Fatty Acid Supplements (Eicosapentaenoic Acid and Docosahexaenoic Acid) in the Secondary Prevention of Cardiovascular DiseaseA Meta-analysis of Randomized, Double-blind, Placebo-Controlled Trials Arch Intern Med. 2012;172(9):686-694. doi:10.1001/archinternmed.2012.262 Figure Legend: Figure 3. Efficacy of omega-3 fatty acid supplements in the secondary prevention of overall cardiovascular events in a random-effects meta-analysis of 14 randomized, double-blind, placebo-controlled trials. RR indicates relative risk. Horizontal lines indicate 95% CIs; gray boxes, the weight of each study. The box area is proportional to the weight of each study. Date of download: 11/3/2017 Copyright © 2012 American Medical Association. All rights reserved.