Heat Shock Proteins in Vascular Disease—A Review

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Presentation transcript:

Heat Shock Proteins in Vascular Disease—A Review T.A. Mehta, J. Greenman, C. Ettelaie, A. Venkatasubramaniam, I.C. Chetter, P.T. McCollum European Journal of Vascular and Endovascular Surgery Volume 29, Issue 4, Pages 395-402 (April 2005) DOI: 10.1016/j.ejvs.2005.01.005 Copyright © 2005 Elsevier Ltd Terms and Conditions

Fig. 1 Two functions of heat shock proteins. Top: as new polypeptide chains (proteins) are being produced by ribosome within the cell, heat shock proteins assist in correct folding of polypeptide chain into functional protein. Presence of heat shock protein (purple) assures that the new protein will assume its functional three-dimensional configuration. Bottom: after stress event, heat shock proteins also assist in refolding or degradation of damaged or denatured proteins.3 European Journal of Vascular and Endovascular Surgery 2005 29, 395-402DOI: (10.1016/j.ejvs.2005.01.005) Copyright © 2005 Elsevier Ltd Terms and Conditions