Monosaccharides, Disaccharides, Polysaccharides and UDP Mechanisms

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Metabolism of Monosaccharides and Disaccharides

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Presentation transcript:

Monosaccharides, Disaccharides, Polysaccharides and UDP Mechanisms

Some Monosaccharides

Formation of Disaccharides (chemical)

Oligosaccharide Antigens in Blood Serotyping

Elastase (glycoprotein)

Lectin-Ligand Interaction in Lymphocyte Turnover and Recruitment H COH 2 HCOH H COOH HCOH OH O H OH NH–CO-CH H 3 N-Acetylneuraminic acid (Neu5AC) (a sialic acid)

Oligosaccharides in Recognition and Adhesion

Lectin on H. pylori Binds to Le Causing Ulcer

Degradation of Di- and Polysaccharides Enzymopathies: Fructosuria (fructokinase) Fructose intolerance (Fru-1-P-aldolase) Lactose intolerance (lactase deficiency) Galactosaemie (galactokinase, galactose 1-P uridyl transferase, UDP-galactose 4- epimerase)

Formation of NDP-sugars (e.g. UDP-glucose)

Galactose metabolism Galactose 1-phosphate NADPH Aldose reductase NADP

Synthesis of Di- and Polysaccharides

N-Glycosylation in the Endoplasmic Reticulum

Vitamin C Synthesis