B. Breathing becomes unstable during sleep at high altitudes in most normal individuals. The upper trace shows an example of a Cheyne-Stokes breathing.

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B. Breathing becomes unstable during sleep at high altitudes in most normal individuals. The upper trace shows an example of a Cheyne-Stokes breathing pattern in a healthy person, during the first night after arriving at an altitude of 17,700 feet, where the low partial pressure of oxygen in the air reduces the blood SaO2 to approximately 75 to 80%. Repeated cycles of waxing and waning ventilation are separated by periods of apnea. Administration of supplemental oxygen results in a rapid return to a normal respiratory pattern. This abnormal pattern disappears in most people after they have acclimated to the altitude. (Reproduced, with permission, from Lahiri et al. 1984.) Source: The Sensory, Motor, and Reflex Functions of the Brain Stem, Principles of Neural Science, Fifth Editon Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available at: https://neurology.mhmedical.com/DownloadImage.aspx?image=/data/Books/1049/kan_ch45_f010.png&sec=59145218&BookID=1049&ChapterSecID=59138677&imagename= Accessed: November 04, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved