The fraction of drug absorbed using the Wagner–Nelson method may be used to distinguish between the first-order drug absorption rate of a conventional.

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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Presentation transcript:

The fraction of drug absorbed using the Wagner–Nelson method may be used to distinguish between the first-order drug absorption rate of a conventional (immediate-release) dosage form (A) and an extended-release dosage form (C). Curve B represents an extended-release dosage form with zero-order absorption rate. Source: Modified-Release Drug Products and Drug Devices, Applied Biopharmaceutics & Pharmacokinetics, 7e Citation: Shargel L, Yu AC. Applied Biopharmaceutics & Pharmacokinetics, 7e; 2016 Available at: http://accesspharmacy.mhmedical.com/DownloadImage.aspx?image=/data/books/1592/sha_ch19_f014.png&sec=100674294&BookID=1592&ChapterSecID=100674031&imagename= Accessed: November 04, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved