Effectiveness Dose Response – Endpoints - Effective Concentrations

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Presentation transcript:

Effectiveness Dose Response – Endpoints - Effective Concentrations - Health Effects - Routes of Entry Physical Characteristics – e.g. particle size, yield Variables – Environmental - Motivation Modeling and Simulation

Routes of Entry Inhalation – Lower respiratory (1-5 microns) - Upper respiratory (1-100 microns) Eye effects – large and small particles, liquid Cutaneous – skin effects, large particles, liquid

Solvents and Propellants (examples) Dymel Blend Iso-butane Nitrogen Carbon dioxide Solvents 1,4 Dioxane 1,1,1,trichloroethane Isopropyl alcohol Methyl isobutyl ketone Methylene Chloride Trichloroethylene Ethanol Soy oil Propylene glycol Water

NL Modeling/Simulation FOR OFFICIAL USE ONLY NL Modeling/Simulation Computer simulations predict the effects from the dispersion of NL chemical devices Analysis (e.g., Monte Carlo simulation) provides assessment of NL system feasibility