The natural history of soy allergy

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Presentation transcript:

The natural history of soy allergy Jessica H. Savage, MD, Allison J. Kaeding, BS, Elizabeth C. Matsui, MD, MHS, Robert A. Wood, MD Journal of Allergy and Clinical Immunology Volume 125, Issue 3, Pages 683-686 (March 2010) DOI: 10.1016/j.jaci.2009.12.994 Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Soy allergy resolution over time. The graph represents the Kaplan-Meier survival curve for development of tolerance to soy over time with the 95% CI. Journal of Allergy and Clinical Immunology 2010 125, 683-686DOI: (10.1016/j.jaci.2009.12.994) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Trend in soy IgE levels over time by final soy allergy status. Scatter plots show all soy IgE levels recorded by age (n = 443). A, All values in the group with persistent soy allergy (n = 269). B, All values in the group that eventually resolved their soy allergy (n = 174). Nonparametric smoothed curves show the trend in soy IgE levels over time. Journal of Allergy and Clinical Immunology 2010 125, 683-686DOI: (10.1016/j.jaci.2009.12.994) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Relationship of peak soy IgE level and resolution of soy allergy. Survival curves for each stratum of peak soy IgE level are shown. Number of patients in each stratum: less than 5 kU/L (n = 38), 5 to 9.9 kU/L (n = 20), 10 to 49.9 kU/L (n = 37), and 50 kU/L or greater (n = 27). Journal of Allergy and Clinical Immunology 2010 125, 683-686DOI: (10.1016/j.jaci.2009.12.994) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions