An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom  A.J. Bradley, J.E. Breen, B. Payne, V. White, M.J. Green  Journal of Dairy Science  Volume 98, Issue 3, Pages 1706-1720 (March 2015) DOI: 10.3168/jds.2014-8332 Copyright © 2015 American Dairy Science Association Terms and Conditions

Figure 1 Illustration of the survival of cows to the first case of clinical mastitis in each of the treatment groups. Cows in the unvaccinated group acted as negative controls and did not receive any vaccinations. Cows recruited to the label group were vaccinated at 45d before the estimated date of calving (based on herd records), 35d later, and 52d postcalving. Cows recruited to the rolling group were vaccinated on the day of recruitment (d 0), 28d later (d 28), 62d thereafter (d 90), and then every 90d until the end of the study. No significant differences were identified between the treatment groups. Journal of Dairy Science 2015 98, 1706-1720DOI: (10.3168/jds.2014-8332) Copyright © 2015 American Dairy Science Association Terms and Conditions

Figure 2 An illustration of the effect of vaccination on milk yield recorded on each of the first 4 DHI test-days (1st to 4th) occurring in the first 120d of lactation. Cows in the unvaccinated group acted as negative controls and did not receive any vaccinations. Cows recruited to the label group were vaccinated at 45d before the estimated date of calving (based on herd records), 35d later, and 52d postcalving. Cows recruited to the rolling group were vaccinated on the day of recruitment (d 0), 28d later (d 28), 62d thereafter (d 90), and then every 90d until the end of the study. a,bDifferent letters within test-day groups are significantly different (P<0.05). Error bars denote SE. Journal of Dairy Science 2015 98, 1706-1720DOI: (10.3168/jds.2014-8332) Copyright © 2015 American Dairy Science Association Terms and Conditions