Volume 151, Issue 4, Pages (April 2017)

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Volume 151, Issue 4, Pages 764-775 (April 2017) Can High-flow Nasal Cannula Reduce the Rate of Endotracheal Intubation in Adult Patients With Acute Respiratory Failure Compared With Conventional Oxygen Therapy and Noninvasive Positive Pressure Ventilation? Yue-Nan Ni, MM, Jian Luo, MD, He Yu, MD, Dan Liu, MD, Zhong Ni, MD, Jiangli Cheng, MD, Bin-Miao Liang, MD, Zong-An Liang, MD CHEST Volume 151, Issue 4, Pages 764-775 (April 2017) DOI: 10.1016/j.chest.2017.01.004 Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 1 Study flow. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 2 Risk of bias. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 3 Risk of bias summary. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 4 Publication bias. COT = conventional oxygen therapy; HFNC = high-flow nasal cannula; NIPPV = noninvasive positive pressure ventilation. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 5 Endotracheal intubation. M-H = Mantel-Haenszel. See Figure 4 legend for expansion of other abbreviations. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 6 ICU mortality. See Figure 4 and 5 legends for expansion of abbreviations. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 7 ICU length of stay. IV = inverse variance. See Figure 4 legend for expansion of other abbreviations. CHEST 2017 151, 764-775DOI: (10.1016/j.chest.2017.01.004) Copyright © 2017 American College of Chest Physicians Terms and Conditions