Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination  Yoko Warabi, Yoh Matsumoto, Hideaki Hayashi  Journal of the Neurological Sciences  Volume 252, Issue 1, Pages 57-61 (January 2007) DOI: 10.1016/j.jns.2006.10.008 Copyright © 2006 Elsevier B.V. Terms and Conditions

Fig. 1 HLA analysis in 10 NMO and 15 MS, and 36 healthy subjects. (A) Unexpectedly, the frequency of DRB1⁎1501 allele, which is known as a major HLA allele of MS patients, did not differ between our MS patients and healthy subjects, or between MS and NMO. N.S. indicated not significant. (B) DPB1⁎0501 allele, which has been reported to be associated with NMO, was carried significantly more frequently by the MS group than by healthy subjects (p=0.03). Journal of the Neurological Sciences 2007 252, 57-61DOI: (10.1016/j.jns.2006.10.008) Copyright © 2006 Elsevier B.V. Terms and Conditions