Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study Dr Natasha Lelijveld, PhD, Andrew Seal, PhD,

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Presentation transcript:

Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study Dr Natasha Lelijveld, PhD, Andrew Seal, PhD, Prof Jonathan C Wells, PhD, Jane Kirkby, PhD, Charles Opondo, PhD, Emmanuel Chimwezi, Dip, James Bunn, MRCP, Robert Bandsma, PhD, Prof Robert S Heyderman, PhD, Prof Moffat J Nyirenda, PhD, Marko Kerac, MRCPCH The Lancet Global Health Volume 4, Issue 9, Pages e654-e662 (September 2016) DOI: 10.1016/S2214-109X(16)30133-4 Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 1 Recruitment of the case group Flow diagram for showing recruitment, starting with original recruitment in 2006 for the PRONUT study,10 followed by 1-year follow up in the FuSAM study,11 and the present follow-up (ChroSAM). The Lancet Global Health 2016 4, e654-e662DOI: (10.1016/S2214-109X(16)30133-4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 2 Time-to-death analysis Kaplan-Meier time-to-death curve showing probability of death for all children in the case group (A) and probability of death for children stratified by HIV serostatus (B). Numbers in parentheses are numbers of deaths. The Lancet Global Health 2016 4, e654-e662DOI: (10.1016/S2214-109X(16)30133-4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions

Figure 3 Changes in anthropometry Graphs show modelled means for WAZ (A) and HAZ (B) for siblings and cases at 1 and 7 years post-discharge. WAZ=weight-for-age Z score. HAZ=height-for-age Z score. The Lancet Global Health 2016 4, e654-e662DOI: (10.1016/S2214-109X(16)30133-4) Copyright © 2016 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY license Terms and Conditions