Proteins The most important biochemicals in cells are proteins (enzymes) Protect organisms from disease Extract energy from food Move essential cellular.

Slides:

Advertisements

Similar presentations

From: Protein Data Bank PDB ID: 1B0E Kalus, W., Zweckstetter, M., Renner, C., Sanchez, Y., Georgescu, J., Grol, M., Demuth, D., Schumacher, R., Dony, C.,

Advertisements

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Concept 5.4: Proteins have many structures, resulting in a wide range of functions.

Protein Structure & Function

Proteins & Nucleic Acids Images taken without permission from

1. Primary Structure: Polypeptide chain Polypeptide chain Amino acid monomers Peptide linkages Figure 3.6 The Four Levels of Protein Structure.

Proteins Structures Primary Structure.

Doris Lee Even Zheng Joanna Tang Kiki Jang Rachel Zhang Vincent Ma.

Levels of Protein Structure Peptide/Protein Formation Peptide: small, up to 50 AA Proteins: large, several 100 AA and/or multiple peptide chains.

Biomolecules: Nucleic Acids and Proteins

7.5: PROTEINS Proteins Function Structure. Function 7.5.4: State four functions of proteins, giving a named example of each. [Obj. 1] Proteins are the.

 Proteins have many different functions in the body  Structure – proteins help provide structure and support, make up muscles and bones.

7.4/14.1 PROTEINS. Protein’s have 4 levels of Structure: 1. Primary Structure = the order of amino acids that make up the polypeptide; amino acids are.

PROTEINS. Learning Outcomes: B4 - describe the chemical structure of proteins List functions of proteins Draw and describe the structure of an amino acid.

Proteins!. Proteins Proteins account for more than 50% of the dry mass of most cells Monomer: amino acids 20 amino acids used in cells Central carbon.

Proteins Multipurpose molecules Proteins Most structurally & functionally diverse group of biomolecules Function: involved in almost everything.

THE STRUCTURE AND FUNCTION OF MACROMOLECULES Proteins - Many Structures, Many Functions 1.A polypeptide is a polymer of amino acids connected to a specific.

Proteins… Let’s Review…… then….. Let’s discover proteins…. PollEv.com/tinalambiase209.

PROTEIN FUNCTIONS. PROTEIN FUNCTIONS (continued)

5.4: Proteins Introduction

Proteins A protein is a compound made of small carbon compounds called AMINO ACIDS There are 20 different kinds of AMINO ACIDS.

AP Biology Proteins AP Biology Proteins Multipurpose molecules.

PROTEINS L3 BIOLOGY. FACTS ABOUT PROTEINS: Contain the elements Carbon, Hydrogen, Oxygen, and NITROGEN Polymer is formed using 20 different amino acids.

Haemoglobin: Structure and Formation of Proteins 1.1.2, a, b,c.

3S: Proteins Shireen Rudina. What do proteins do? Structure – Collagen in skin, keratin in hair and nails Signaling between cells Defend against disease.

Proteins Structures and Functions. What? A series of amino acids in a polypeptide chain Produced from the coding in the DNA of the nucleus Makes up.

PROTEINS Proteins Composed mainly of –Carbon –Hydrogen –Nitrogen.

Proteins Tertiary Protein Structure of Enzyme Lactasevideo Video 2.

19.5 Protein Structure: Tertiary and Quaternary Levels

Four Levels of Protein Structure

Protein Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form in a biologically functional.

Amino Acids, Proteins & Enzymes Chapter 16

Functional Variety of Proteins

PROTEINS and ENZYMES!.

Proteins account for more than 50% of the dry mass of most cells

Proteins have a very wide range of functions in living organisms.

Protein Structure.

(4) Genes and proteins in health and disease

Amino Acids and Proteins

Proteins… Let’s Review…… then….. Let’s discover proteins….

Amino Acids, Proteins, and Enzymes

Proteins – V2.

Proteins clockwise: Rubisco — most important protein on the planet?

Protein Structure Amino Acids Polypeptide Levels of Structure

Transport proteins Transport protein Cell membrane

From: Protein Data Bank PDB ID: 1B0E

Protein Structure and Examples

11/13/ :55 AM Proteins 2.4 © 2007 Microsoft Corporation. All rights reserved. Microsoft, Windows, Windows Vista and other product names are or may.

Proteins Topic 7.5.

Macromolecules Part 2 Unit 1 Chapter 5.

Proteins account for more than 50% of the dry mass of most cells

See Page 563 Essential amino acids must be obtained from the diet.

Proteins Topic 7.5.

Study Question: What are enzymes?

Enzymes and Proteins.

Chapter 19: Proteins.

Protein Structure Chapter 14.

Proteins account for more than 50% of the dry mass of most cells

Proteins Genetic information in DNA codes specifically for the production of proteins Cells have thousands of different proteins, each with a specific.

Unit 7: Molecular Genetics 7.6 Proteins

Protein Structure and Examples

2.4 - Proteins.

Presentation transcript:

Proteins The most important biochemicals in cells are proteins (enzymes) Protect organisms from disease Extract energy from food Move essential cellular components Responsible for vision, taste and smell Proteins are the molecular machinery of the cell. Day 1

Proteins Day 1 Proteins are made of amino acids (aa) The base structure is the same, but each a.a. has a different side chain There are 20 a.a. in humans Each has different properties Day 1

Globular Proteins Are compact, roughly spherical structures with folds and grooves Enzymes: globular proteins that speed up biochemical reactions Ex: Hemoglobin, antibodies, and hormones Carry most of the work done by cells Day 1

Globular Proteins Day 1

Fibrous Proteins Structural components of cells and tissue are made of proteins that form fibers. The fibrous proteins are the cables, girders, bricks and mortar of organisms. Day 1

Collagen Silk Fiber

Proteins Day 1 A protein has 4 structure categories: Primary: Basic linkage of amino acids Carbon of one links to N of other in chain Secondary: alpha helix and beta pleated sheet Both use hydrogen bonding Tertiary: Intermolecular bonding Salt bridge, hydrophilic/hydrophobic, polar/nonpolar, disulfur linkage Quaternary: protein-protein interaction Day 1

Primary Structure Day 1

Making a protein We are going to make a protein called Vasopressin (ADH) It is involved in kidney function, formation of memory, and can increase blood pressure The sequence of amino acids is cys-tyr-phe-gln-asn-cys-pro-arg-gly Each team will make 1 amino acid and we will link them together. Day 1

Making a protein questions Questions to ask: What happens when 1 amino acid links to another? Ans: Water is released, peptide bond formed 2. Looking at the linkage of only 9 amino acids, how complicated do you think a model of a typical protein (100s – 1000s of amino acids) would be? Day 1

2°: The Helix

2°: Pleated Sheet

Tertiary Structure Check out http://fold.it Each protein has a unique 3D shape called tertiary structure Results from the bends and folds the peptide chain makes to achieve the lowest possible energy. Check out http://fold.it Bonding is from sidechain (R group) interactions

Tertiary Structure Hydrogen Bond Salt Bridge Hydrophobic Bond Disulfide Bond

Quaternary Structure Binds several different proteins together This can be through a variety of interactions (sulfur linkages, hydrogen bonding, etc) Often a process in the body needs several proteins coordinated together to work