Medical Technology Week 2 Room 217 with Miss Charles Objectives: SWBAT – identify the function of erythrocytes, leukocytes, and platelets. SWBAT – Describe the composition of blood.

Medical Technology Week 2 Room 217 with Miss Charles Objectives: SWBAT – explain the role of plasma in the blood. SWBAT – explain the role of thrombocytes in the blood.

Medical Technology Week 2 Room 217 with Miss Charles Objectives: SWBAT – describe the different kinds of anemia and explain the implications of elevated bilirubin levels in the blood.

Medical Technology Week 2 Room 217 with Miss Charles Objectives: SWBAT – explain the purpose and use of hemotologic reference intervals.

Medical Technology Week 2 Room 217 with Miss Charles Objectives: SWBAT – apply my knowledge of the blood and its components to infer what could be wrong with a sick person?

What are stems cells? Epithelial fibroblast cells Cells that can turn into any kind of body cell Cells that turn into erythrocytes Brain Cells Take out your phone and join the poll! Go to pollev.com/charlesbiology or text CHARLESBIOLOGY to 37607

What types are foods should you have in your diet that are vital for RBC production? Foods rich in Magnesium Foods rich in Potassium and Calcium Foods rich in Iron and Vitamins E, B2, B12, and B3 Foods rich in omega-3 fatty acids Take out your phone and join the poll! Go to pollev.com/charlesbiology or text CHARLESBIOLOGY to 37607

Let’s review what we have learned last week… But first, copy down today’s objectives: SWBAT – identify the function of erythrocytes, leukocytes, and platelets. SWBAT – Describe the composition of blood. Take out your phone and join the poll! Go to pollev.com/charlesbiology or text CHARLESBIOLOGY to 37607

45% of the blood volume is composed of… Erythrocytes Leukocytes Plasma Platelets Go to pollev.com/charlesbiology or text CHARLESBIOLOGY to 37607.

What disease does the presence of erythroblast cells indicate? This is an open ended question, so please type out your response!

Hematopoiesis occurs in what part of the body? This is an open ended question, so please type out your response!

Put the following terms in sequential order WRT to erythropoiesis… RBC -> stem cell -> erythroblast Stem cell -> RBC -> erythroblast Erythroblast -> stem cell -> RBC Stem cell -> erythroblast -> RBC

Differentiation Differentiation occurs when a stem cell decides what kind of body cell it is going to be. In the case of erythropoiesis, erythroblast cells influence stem cells to differentiate into becoming red blood cells. An erythroblast is the middle stage between stem cell and red blood cell.

Composition Of Blood I Blood is composed of a liquid called plasma, and of cellular elements including leukocytes, platelets or thrombocytes, and erythrocytes. The normal adult has about 6 liters of blood which composes 7%-8% of the total body weight. Plasma makes up about 55% of the blood volume, erythrocytes make up about 44% of the blood volume, and 1% of the blood volume is composed of leukocytes and platelets. Changes in the ratio of these blood elements are often the first sign of disease. Laboratory tests measure deviations from normal levels of blood components to detect diseased tissues.

What’s in your blood?

What is plasma? The main component of plasma is water which includes: Dissolved ions Proteins Carbohydrates Fats Hormones Vitamins Enzymes Blood plasma acts as a transport medium for cell nutrients and metabolites . For example, hormones made in one tissue are transported by the blood to other target tissues in the body. The ions needed for normal cell function include: Calcium Sodium Potassium Chloride Magnesium Hydrogen

What are Thrombocytes or Platelets? Round disc-shaped structures that aide in the clotting of blood. Play an important role in primary hemostasis by adhering to the wall of a ruptured (broken) blood vessel and aggregating (grouping up and clumping together) to form a platelet plug over the injury. Platelets are also important for secondary hemostasis because they provide platelet phospholipids that are important for the activation of coagulation proteins. [throm-buh-sahyt]

Hemostasis The process or number of processes responsible for stopping the flow of blood. This is essentially what keeps you from bleeding to death.  [hee-muh-stey-sis]

Let’s talk about Bili… Bilirubin an orange-yellow pigment formed in the liver by the breakdown of hemoglobin and excreted in bile. Yellowing is associated with the accumulation of the bilirubin in the skin, most often caused by liver and gallbladder disorders. In the case of liver disease, the bilirubin level in the blood increases indicating the organ disease. *However, hemolytic anemia may cause bilirubin levels to rise because of the increased metabolism of hemoglobin.

Common Types of Anemia I Iron-deficiency anemia. If you don't have enough iron in your body, your body won't be able to make enough red blood cells. Iron-deficiency anemia is the most common form of anemia. Among the causes of iron deficiency are a diet low in iron, a sudden loss of blood, a chronic loss of blood (such as from heavy menstrual periods), or the inability to absorb enough iron from food.

Common Types of Anemia II Sickle cell anemia. In this inherited disease, the red blood cells are shaped like half moons rather than the normal indented circles. This change in shape can make the cells "sticky" and unable to flow smoothly through blood vessels. This causes a blockage in blood flow. This blockage may cause acute or chronic pain and can also lead to infection or organ damage. Sickle cells die much more quickly than normal blood cells—in about 10 to 20 days instead of 120 days—causing a shortage of red blood cells.

Common Types of Anemia III Normocytic anemia. This type of anemia happens when your red blood cells are normal in shape and size, but you don't have enough of them to meet your body's needs. Diseases that cause this type of anemia are usually long-term conditions, like kidney disease, cancer, or rheumatoid arthritis. [Nor-muh-cytic]

Common Types of Anemia IV Hemolytic anemia. This type of anemia happens when red blood cells are destroyed by an abnormal process in your body before their lifespan is over. As a result, your body doesn't have enough red blood cells to function, and your bone marrow cannot make enough to keep up with demand. [he-moe-li-tic]

Common Types of Anemia V Fanconi anemia. This is a rare inherited disorder in which your bone marrow isn't able to make enough of any of the components of blood, including red blood cells. Children born with this disorder often have serious birth defects because of the problems with their blood and may develop leukemia