Fig. 1 (A) The figure shows the placement of the 1 cm thick sagittal slices in <sup>31</sup>P-MRS. According to their position, slices were assigned to.

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Presentation transcript:

Fig. 1 (A) The figure shows the placement of the 1 cm thick sagittal slices in <sup>31</sup>P-MRS. According to their position, slices were assigned to contain mainly cortical tissue, mainly white matter or mixed grey and white matter. Below the scan a typical <sup>31</sup>P-spectrum with the peaks for phosphodiesters (PDE), inorganic phosphate (Pi), phosphomonoesters (PME), phosphocreatine (PCr) and the three peaks for ATP is shown. (B) The figure shows where the voxels were placed for <sup>1</sup>H-MRS. The size of the voxels was 3 × 3 × 2 cm<sup>3</sup>. The voxel were placed at the level of the basal ganglia to include as much white matter as possible and to minimize contribution from CSF. A typical <sup>1</sup>H-spectrum with peaks for N-acetyl-aspartate (NAA), choline (Cho) and creatine (Cre) is shown below the scan. From: Association between cortical metabolite levels and clinical manifestations of migrainous aura: an MR-spectroscopy study Brain. 2007;130(12):3102-3110. doi:10.1093/brain/awm165 Brain | © The Author (2007). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org