From: A Mean-field Model of Ventricular Muscle Tissue Date of download: 11/7/2017 Copyright © ASME. All rights reserved. From: A Mean-field Model of Ventricular Muscle Tissue J Biomech Eng. 2012;134(7):071003-071003-13. doi:10.1115/1.4006850 Figure Legend: Force-Calcium relationships. (a), Experimentally measured F-pCa relationship in rat cardiac-muscle tissue(skinned). The sarcomere length was maintained at 2.05μm. The horizontal-axis is the log of activator [Ca] in μM, the vertical-axis is the normalized force. The mean measured force is plotted as diamonds, the error bars show the standard error. The solid line is the Hill function fit. (b), The F-pCa profile predicted by the proposed model (FF mode) using Eq. to model ψ variation (solid line) as function of [Ca], the normalized predicted force is given by the broken line. The FF mode is the most similar setup to the experiment. (c), Overlap of Hill function fit in (a) (solid line), with model predicted Force (broken line) for the range of [Ca] values. Fig. (a) reproduced from Fig. of Rice [].