Copyright © 2002 American Medical Association. All rights reserved.

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Copyright © 2002 American Medical Association. All rights reserved. From: Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients With Isolated Systolic Hypertension and Left Ventricular HypertrophyA Losartan Intervention For Endpoint Reduction (LIFE) Substudy JAMA. 2002;288(12):1491-1498. doi:10.1001/jama.288.12.1491 Date of download: 11/8/2017 Copyright © 2002 American Medical Association. All rights reserved.

Copyright © 2002 American Medical Association. All rights reserved. From: Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients With Isolated Systolic Hypertension and Left Ventricular HypertrophyA Losartan Intervention For Endpoint Reduction (LIFE) Substudy JAMA. 2002;288(12):1491-1498. doi:10.1001/jama.288.12.1491 Figure Legend: CI indicates confidence interval. Date of download: 11/8/2017 Copyright © 2002 American Medical Association. All rights reserved.

Copyright © 2002 American Medical Association. All rights reserved. From: Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients With Isolated Systolic Hypertension and Left Ventricular HypertrophyA Losartan Intervention For Endpoint Reduction (LIFE) Substudy JAMA. 2002;288(12):1491-1498. doi:10.1001/jama.288.12.1491 Figure Legend: CI indicates confidence interval. Percentage of patients with firstevent are shown for stroke and myocardial infarction. Date of download: 11/8/2017 Copyright © 2002 American Medical Association. All rights reserved.

Copyright © 2002 American Medical Association. All rights reserved. From: Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients With Isolated Systolic Hypertension and Left Ventricular HypertrophyA Losartan Intervention For Endpoint Reduction (LIFE) Substudy JAMA. 2002;288(12):1491-1498. doi:10.1001/jama.288.12.1491 Date of download: 11/8/2017 Copyright © 2002 American Medical Association. All rights reserved.

Copyright © 2002 American Medical Association. All rights reserved. From: Effects of Losartan on Cardiovascular Morbidity and Mortality in Patients With Isolated Systolic Hypertension and Left Ventricular HypertrophyA Losartan Intervention For Endpoint Reduction (LIFE) Substudy JAMA. 2002;288(12):1491-1498. doi:10.1001/jama.288.12.1491 Figure Legend: *Titration upward encouraged if sitting systolic pressure was 140mm Hg or higher, but mandatory if it was 160 mm Hg or higher. Addition ofangiotensin-converting enzyme inhibitors, other angiotensin II AT1-antagonists,or other β-blockers prohibited. Date of download: 11/8/2017 Copyright © 2002 American Medical Association. All rights reserved.