Volume 107, Issue 4, Pages (April 1995)

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Volume 107, Issue 4, Pages 1089-1094 (April 1995) Utility of an Implantable Right Ventricular Oxygen Saturation-Sensing Pacemaker for Ambulatory Cardiopulmonary Monitoring Chu-Pak Lau, MD, FCCP, Yau-Ting Tai, MBBS, FCCP, Iris S.F Lee, RN, Mark Erickson, BS, Charles Yerich, BS CHEST Volume 107, Issue 4, Pages 1089-1094 (April 1995) DOI: 10.1378/chest.107.4.1089 Copyright © 1995 The American College of Chest Physicians Terms and Conditions

Figure 1 Anteroposterior (AP) and left anterior oblique (LAO) radiographs of a patient during implantation of an oxygen-driven dual-chamber rate-adaptive pacemaker. The oxygen sensor was shown up radiographically as three radiopaque dots (lower arrows) proximal to the ventricular pacing electrode. A 6F multipurpose catheter (upper arrow) was advanced from the femoral vein into the right ventricle for simultaneous blood sampling. CHEST 1995 107, 1089-1094DOI: (10.1378/chest.107.4.1089) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

Figure 2 Experiment set-up to investigate the usefulness of an implanted oxygen sensor to predict cardiopulmonary parameters. The pieces of equipment include the following: (1) a metabolic cart to sample breath-by-breath gaseous exchanges; (2) a continuous-wave Doppler to measure CO by sampling ascending aortic blood flow; (3) a pulse oximeter to measure SaO2; and (4) an implanted oxygen sensor and pacemaker giving telemetry-derived oxygen saturation data from the right ventricle. See text for details of data analysis. CHEST 1995 107, 1089-1094DOI: (10.1378/chest.107.4.1089) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

Figure 3 Changes in telemeter-derived SvO2 during exercise in seven patients (901 to 908). Patient 906 had suboptimal sensor function and was excluded from exercise. CHEST 1995 107, 1089-1094DOI: (10.1378/chest.107.4.1089) Copyright © 1995 The American College of Chest Physicians Terms and Conditions

Figure 4 Correlation between CO estimated from Vo2, SvO2, and SaO2 arterial oxygen saturation (Est-CO in arbitrary units) and directly measured CO from Doppler (Dop-CO). Each dotted line shows 1 SEM from the mean. CHEST 1995 107, 1089-1094DOI: (10.1378/chest.107.4.1089) Copyright © 1995 The American College of Chest Physicians Terms and Conditions