PET imaging can also be applied in the preclinical setting to increase our understanding of the underlying biology, as well as inform the design of clinical.

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Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Copyright © 2004 The McGraw-Hill Companies, Inc. All rights reserved.

Presentation transcript:

PET imaging can also be applied in the preclinical setting to increase our understanding of the underlying biology, as well as inform the design of clinical imaging studies. In this example, an FDG-PET image is acquired of a subcutaneous tumor (ME-180, cancer cervix model). The accumulation of FDG is seen to be quite heterogeneous within the mass. The generation of such a high-resolution image would be challenging on a clinical PET scanner because of the detector geometry. The use of a preclinical system helps to inform our understanding of a clinical FDG image and how it relates to the very-high-resolution microscopy demonstrated in Figure 14–1A. (Image courtesy of STTARR Facility, Toronto, Canada.) Source: Imaging in Oncology, The Basic Science of Oncology, 5e Citation: Tannock IF, Hill RP, Bristow RG, Harrington L. The Basic Science of Oncology, 5e; 2016 Available at: http://hemonc.mhmedical.com/DownloadImage.aspx?image=/data/Books/1791/tanbas5_Ach14_f009.png&sec=124304740&BookID=1791&ChapterSecID=124304688&imagename= Accessed: November 09, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved