From: Mercury Poisoning Presenting as Sporadic Creutzfeldt–Jakob Disease: A Case Report Ann Intern Med. 2015;162(6):462-463. doi:10.7326/L15-5067 Figure Legend: A and B. Striking, relatively symmetric, bilateral, cortical gray matter involvement based on diffusion-weighted imaging and fluid-attenuated inversion recovery images 3 mo after symptom onset. C and D. Hyperintense diffusion-weighted imaging signals and hypointense apparent diffusion coefficient signals in subcortical gray matter (caudate nucleus) and cortical gray matter 5 mo after symptom onset. E. No significant improvement on diffusion-weighted imaging after chelation therapy. F. Brain atrophy at 2-y follow-up. Date of download: 11/9/2017 Copyright © American College of Physicians. All rights reserved.