Oxygenation and plasma endothelin‐1 concentrations in healthy horses recovering from isoflurane anaesthesia administered with or without pulse‐delivered.

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Oxygenation and plasma endothelin‐1 concentrations in healthy horses recovering from isoflurane anaesthesia administered with or without pulse‐delivered inhaled nitric oxide Tamara Grubb, Anna Edner, Jan HM Frendin, Pia Funkquist, Anneli Rydén, Görel Nyman Veterinary Anaesthesia and Analgesia Volume 40, Issue 6, Pages e9-e18 (November 2013) DOI: 10.1111/j.1467-2995.2012.00735.x Copyright © 2013 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure f1 Arterial and mixed venous oxygen tension (PaO2, PvO2) and saturation (SaO2, SvO2) in horses recovering from anaesthesia receiving intraoperative pulse‐delivered iNO (Nitric oxide horses) and those not receiving intraoperative iNO (Control horses). Data presented as mean ± SD. *Significantly different between groups; +Significantly different from Time 2 (baseline for this study). Data were collected every 2 minutes from Time 2 for 10 minutes (Times 4–10) and then every 5 minutes (Times 15–30) for a total data collection period of 30 minutes. Veterinary Anaesthesia and Analgesia 2013 40, e9-e18DOI: (10.1111/j.1467-2995.2012.00735.x) Copyright © 2013 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure f2 Shunt fraction (Qs/Qt) in horses recovering from anaesthesia receiving intraoperative pulse‐delivered iNO (Nitric oxide horses) and those not receiving intraoperative NO (Control horses). Data presented as mean ± SD. *Significantly different between groups; +Significantly different from Time 2 (baseline for this study). Data were collected every 2 minutes from Time 2 for 10 minutes (Times 4–10) and then every 5 minutes (Times 15–30) for a total data collection period of 30 minutes. Veterinary Anaesthesia and Analgesia 2013 40, e9-e18DOI: (10.1111/j.1467-2995.2012.00735.x) Copyright © 2013 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions

Figure f3 Plasma endothelin (ET‐1) concentrations (mean ± SD) in horses recovering from anaesthesia receiving intraoperative pulse‐delivered iNO (Nitric oxide horses) and those not receiving intraoperative NO (Control horses). Data presented as mean ± SD. *Significantly different between groups; +Significantly different from Time 2 (baseline for this study). Data were collected every 2 minutes from Time 2 for 10 minutes (Times 4–10) and then every 5 minutes (Times 15–30) for a total data collection period of 30 minutes. Veterinary Anaesthesia and Analgesia 2013 40, e9-e18DOI: (10.1111/j.1467-2995.2012.00735.x) Copyright © 2013 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Terms and Conditions