Pathogenesis of CKD-MBD and renal osteodystrophy Pathogenesis of CKD-MBD and renal osteodystrophy.aThese adaptations are lost as kidney failure progresses. (From Hudson JQ, Wazny LD. Chronic kidney disease. In: DiPiro JT, Talbert RL, Yee GC, et al., eds. Pharmacotherapy: A Pathophysiologic Approach, 9th ed. New York, NY: McGraw-Hill Education, 2014:638, with permission.) Source: Chronic and End-Stage Renal Disease, Pharmacotherapy Principles & Practice, 4e Citation: Chisholm-Burns MA, Schwinghammer TL, Wells BG, Malone PM, Kolesar JM, DiPiro JT. Pharmacotherapy Principles & Practice, 4e; 2016 Available at: https://ppp.mhmedical.com/DownloadImage.aspx?image=/data/books/1793/chis_ch26_f005.png&sec=120651194&BookID=1793&ChapterSecID=120651075&imagename= Accessed: November 10, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved